Table 5.
Results of the genome‐wide methylation studies performed on five of the cases 10. Abbreviations: LGA = low‐grade glioma; Mut. = mutated; WT = wild type; PXA = pleomorphic xanthoastrocytoma; GBM = glioblastoma
| Case No. | 450k array clustering pattern | H3F3A | IDH1 (R132H) | BRAF V600E | Amplifications | Homozygous deletions | Gains | Losses |
|---|---|---|---|---|---|---|---|---|
| 2 | PXA | WT | WT | WT | None | CDKN2A | 5, 7, 9q, 12p, 14q, 16q, 22q | 1, 6, 13q, 14q, 21q |
| 11 | GBM | WT | WT | WT | None | None | 7 | 1p, 3p, 6, 8, 9p, 10p, 13q, 14q, 17p, 22q |
| 12 | PXA | WT | WT | Mut. | None | None | None | None |
| 13 | LGA | WT | WT | Mut. | None | None | None | None |
| 14 | GBM | WT | WT | WT | None | None | None | None |