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Structural disease of small cerebral blood vessels in dementia. A. Arteriolosclerosis in the parietal white matter. The white matter is rarefied and gliotic. B. In another brain with rarefied, gliotic white matter, perivascular spaces are markedly enlarged. C. The overlying cerebral cortex shows severe capillary cerebral amyloid angiopathy (CAA), demonstrated by immunohistochemistry for Aβ42. D. Old hematoma cavity in the subcortical white matter in association with arteriolar CAA.
