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. 2014 Dec 17;25(1):99–107. doi: 10.1111/bpa.12223

Figure 3.

figure

Myelin‐associated glycoprotein (MAG) : proteolipid protein 1 (PLP1) ratio as a measure of the severity of chronic hypoperfusion of the cerebral white matter. In a study of two independent post‐mortem cohorts from Bristol and Oxford, MAG : PLP1 declined significantly with increasing severity of arteriolosclerotic small vessel disease (SVD) (Spearman's test: Bristol P = 0.0003, Oxford P = 0.0009). Note that severity of SVD was scored on a 4‐point scale in the Bristol cohort and on a 12‐point scale 96 in the Oxford cohort. Reproduced with permission from 8.