Table 2.

Univariate and multivariate analyses. Abbreviations: CI = confidence interval; HR = hazard ratio; m = multiple; OS = overall survival; PFS = progression free survival; PS = performance status; s = single

Parameters	Univariate analysis				Multivariate analysis
	PFS		OS		PFS		OS
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
CD68+ %area*	1.08 (1.00–1.15)	0.04	1.04 (0.96–1.12)	0.34	1.14 (0.96–1.38)	0.14	1.09 (0.87–1.35)	0.39
CD163+ %area*	1.06 (0.998–1.12)	0.05	1.03 (0.96–1.09)	0.37	0.95 (0.81–1.12)	0.56	0.93 (0.78–1.11)	0.41
CD204+ %area*	1.06 (0.95–1.18)	0.28	1.04 (0.91–1.16)	0.52	1.01 (0.81–1.24)	0.89	1.09 (0.87–1.35)	0.45
Age (years)*	1.01 (0.96–1.05)	0.63	1.01 (0.96–1.06)	0.53	0.97 (0.92–1.03)	0.42	0.98 (0.91–1.04)	0.43
Sex (male : female)	1.53 (0.68–3.25)	0.28	1.62 (0.64–3.81)	0.29	1.08 (0.91–1.30)	0.09	1.70 (0.59–4.68)	0.31
Number of tumor (m : s)	2.36 (1.13–5.12)	0.02	1.74 (0.80–3.93)	0.15	1.00 (0.86–1.18)	0.03	1.79 (0.68–4.87)	0.23
PS*	1.51 (0.98–2.30)	0.06	2.07 (1.33–3.21)	0.001	1.57 (0.94–2.63)	0.08	2.39 (1.39–4.22)	0.001

*Continuous variables.

P‐value < 0.05 was considered to be statistically significant in bold.