Table 1.
Results
| N = 50 | P‐value | |
|---|---|---|
| Mean Age (SD) | 57.03 (13.14) | |
| Male, n (%) | 33 (66) | |
| DDKT, n (%) | 39 (78) | |
| Concomitant diabetic therapy, n(%) | ||
| Metformin | 32 (64) | |
| GLP‐1 | 5 (10) | |
| DPP‐4 | 12 (24) | |
| Sulfonylurea | 1 (2) | |
| Insulin | 42 (84) | |
| Diabetes Type | ||
| Pre‐existing Type 2 Diabetes | 40 (80) | |
| PTDM | 10 (20) | |
| Immunosuppression Regimen, n(%) | ||
| Tacrolimus | 45 (90) | |
| Mycophenolate mofetil | 47 (94) | |
| Prednisone | 49 (98) | |
| Time from Transplant to Drug initiation (Median, IQR) | 319.5 d (122, 696) | |
| Started within 200 d n (%) | 20 (40) | |
| Started within 365 d n (%) | 30 (60) | |
| eGFR at Drug Initiation (Mean, SD) | 66.7 mL/min | |
| 30‐45 mL/min n(%) | 7 (14) | |
| Change in eGFR (Median, IQR) postinitiation | ||
| 3 mo (IQR) | −1 mL/min (−7.5, 7) | P = .8831 |
| 6 mo (IQR) | 1 mL/min (−8,16) | P = .1478 |
| Change in HgbA1C (Mean, SD) | −0.53% (1.79) | P = .1189 |
| Treated UTI (%) | 7 (14) | |
| Change in Insulin Requirement (Mean, SD) | −3.7 units (22.8) | P = .17 |
Abbreviations: DDKT, deceased donor kidney transplant; DPP‐4, dipeptidyl peptidase 4 inhibitors; eGFR, estimated glomerular filtration rate (mL/min/1.73m2); GLP‐1, glucagon‐like peptide‐1; HgbA1c, haemoglobin A1c; IQR, interquartile range; SD, standard deviation; UTI, urinary tract infection.
a
Excluding patients already on magnesium repletion therapy.