Table 1.
Baseline characteristics
CPAP n = 36 |
Control n = 36 |
P‐value | |
---|---|---|---|
Male sex % | 72% | 83% | .26 |
Age (y) | 63 ± 7 | 61 ± 8 | .24 |
Duration of diabetes (y) | 16 ± 7 | 16 ± 10 | .97 |
Height (m) | 1.74 ± 0.09 | 1.73 ± 0.07 | .72 |
Body weight (kg) | 109 ± 16 | 99 ± 11 | .004 |
Body mass index, BMI (kg/m2) | 36.1 ± 4.7 | 33.1 ± 3.5 | .003 |
Waist circumference (cm) | 119 ± 17 | 115 ± 8 | .21 |
Hip circumference (cm) | 118 ± 12 | 112 ± 11 | .02 |
Neck circumference (cm) | 47 ± 14 | 44 ± 3 | .25 |
Systolic blood pressure (mm Hg) | 141 ± 15 | 141 ± 16 | .98 |
Diastolic blood pressure (mm Hg) | 81 ± 9 | 82 ± 8 | .47 |
Sleep related data | |||
Epworth Sleepiness Scale (ESS) | 7 ± 3 | 8 ± 5 | .24 |
Apnoea‐hypopnoea index (AHI) | 32 (IQR 21‐43) | 34(IQR 22‐49) | .62 |
Laboratory values | |||
HbA1c (mmol/mol) | 64 ± 9 (8.0 ± 0.8) | 65 ± 9 (8.1 ± 0.8) | .81 |
Plasma fasting glucose (mmol/L) | 10.0 ± 2.6 | 9.1 ± 2.1 | .11 |
Plasma creatinine (µmol/L) | 85.5 ± 35.0 | 83.6 ± 20.2 | .77 |
Plasma total‐cholesterol (mmol/L) | 4.2 ± 0.9 | 3.9 ± 0.9 | .26 |
Plasma LDL‐cholesterol (mmol/L) | 2.1 ± 0.8 | 1.8 ± 0.7 | .16 |
Plasma HDL‐cholesterol (mmol/L) | 1.17 ± 0.24 | 1.16 ± 0.35 | .89 |
Lifestyle | |||
Alcohol consumption per week (0‐7 units, 8‐21 units, >21 units) | 84%/8%/8% | 89%/11%/0% | .20 |
Current smokers, n (%) | 3 (8%) | 7 (19%) | .38 |
Late diabetic complications | |||
Nephropathy | |||
Normoalbuminuria | 63% | 64% | .60 |
Microalbuminuria | 34% | 27% | |
Macroalbuminuria | 3% | 9% | |
Autonomic neuropathy | |||
Normal | 24% | 38% | |
Borderline CAN a | 33% | 24% | |
Established CAN a | 43% | 38% | .45 |
Peripheral neuropathy, n (%) | 5 (14%) | 3 (8%) | .43 |
Cardio vascular disease (n) | AMI = 2 | AMI = 3 | – |
TCI = 6 | TCI = 4 | – | |
Use of medication | |||
Metformin | 83% | 78% | .55 |
Other oral antidiabetic drugs (DPP‐4/SGLT‐2/SU) | 23% | 31% | .69 |
Insulin | 61% | 69% | .46 |
GLP‐1 agonist | 58% | 50% | .48 |
Antihypertensive treatment | 94% | 83% | .13 |
Diuretics | 58% | 47% | .35 |
Statin treatment | 79% | 83% | .59 |
Aspirin | 53% | 51% | .91 |
Cardiovascular autonomic neuropathy.