TABLE 3.
TyG indices in evaluating IR in Asian population
| Country | Method of assessement | Number of participants | Aims | Results | Conclusion |
|---|---|---|---|---|---|
| China 27 | TyG index | 6078 persons > 60 years | Development of CVD | 22.01/1000 persons‐year having CVD after 6 years FU | TyG index might predict CVD events |
| China 29 | TyGs: TyG index, TyG‐BMI, TyG‐WC, TG‐WtHR | 105 070 lean adults without HTN | Investigate the association of TyGs with pre‐hypertension | TyGs higher than normaltensive individuals, but only TyG‐BMI, TyG‐WC more significantly. | TyG‐BMI might be accessible in non‐obese preHTN pts |
| China 32 | TyG | 3.745 CAD patients. FU 11 235 persons | Evaluate the prognosis value of TyG index | TyG associated with CV events (HR: 1.34, 95% CI: 1.100‐1.691, p = .005) | TyG maybe predicting outcomes in CAD patients. |
| China 34 | TyG | 4686 subjects, 9 years FU | To investigate the incident hypertension | high TyG associated with increased risk of HTN incidence | TyG can predict the incident HTN. |
| Iran 41 | TyG index, HOMA‐IR | 61 obese persons | Compare TyG with HOMA‐IR | IR :34%, TyG: 61%, there was a relationship between HOMA‐IR and TyG, r = .004, p < .001 | TyG useful, accessible for assess IR |
| Korean National Health and Nutrition Examination 36 | 4 parameters TyG, HOMA‐IR | 11 149 subjects (4777 men) on Survey 2007‐2010 | Compare TyG index and related parameters | ORs of quartile 4 compare with quartile 1:7.6 (6.52‐8.87) for TyG, 12.82 (10.89‐15.10) for TyG‐BMI, 16.29 (13.70‐19.38) for TyG‐WC, and 14.86 (12.53‐17.62) for TyG‐WHtR. | TyG‐BMI was superior to other parameters for IR prediction in clinical settings |
| Korea 37 | TyG index, baPWV | 2560 persons without a history of CAD | Evaluate the relationship with arterial stiffness | TyG index correlate with baPWV r = .224, p < .001 | TyG associated with aterial stiffness |
| Vietnam 38 | TyG, HOMA‐IR, CT Angiography | 166 type 2 diabetic pts | Investigate the association between TyG and CV risk factors | TyG correlated with HOMA‐IR (p < .001). The patients with coronary syndrome had higher TyG. | TyG may be an IR marker and identify high risk of coronary stenoses |
| Vietnam 39 | TyGs, HOMA‐IR | 69 metabolic syndrome pts, 64.9 ± 14 years | Evaluate the TyGs indices in IR | TyGs correlated with HOMA‐IR (r = .488, p < .001), OR: 3.362 (CI 95%, 1.21‐9.30). | TyGs can be used to defining IR in the patients with MS |
Abbreviations: baPWV, brachial‐ankle pulse wave velocity; CT, computerized tomography; CV, cardiovascular; CVD, cardiovascular disease; FU, follow‐up; HOMA‐IR, homeostasis model assessement – insulin resistance; HTN, hypertension; MS, metabolic syndrome; TG‐WtHR, triglyceride‐waist to height ratio; TyG, triglycerid glucose index; TyG‐BMI, triglycerid glucose index‐ body mass index; TyGs, triglyceride glucose indices; TyG‐WC, triglycerid glucose index‐ waist circumference.