Table 1.
Characteristics of infants with RDS, GA 30–36 weeks, and BW> 2 kg by surfactant exposure, 2006–2016.
| Characteristic | Surfactant (N = 25,278) | No surfactant (N = 29,686) |
|---|---|---|
| Discharge year, % | ||
| 2006–2010 | 48 | 41 |
| 2011–2016 | 52 | 59 |
| GA (weeks), % | ||
| 30–33 | 24 | 23 |
| 34–36 | 76 | 77 |
| BW in kilograms, median (IQR) | 2.463 (2.220–2.775) | 2.421 (2.200–2.719) |
| Large for GA, % | 17 | 15 |
| Inborn, % | 81 | 87 |
| Cesarean section, % | 66 | 63 |
| Maternal race/ethnicity, % | ||
| White | 69 | 61 |
| Black | 9 | 13 |
| Hispanic | 19 | 22 |
| Other | 3 | 4 |
| Male sex, % | 66 | 62 |
| Antenatal steroids, % | 30 | 33 |
| Highest level of respiratory support on postnatal day 0–2, % | ||
| Room air, no support | <1 | 5 |
| Noninvasive supporta | 48 | 86 |
| Conventional MV | 49 | 9 |
| High-frequency MV | 3 | 1 |
| Max FiO2 on postnatal day 0–2, median (IQR) | 35 (30–50) | 30 (21–35) |
| Type of surfactant received, % | ||
| Beractant | 30 | N/A |
| Calfactant | 22 | |
| Poractant alfa | 48 | |
GA gestational age, BW birth weight, IQR interquartile range, FiO2 fraction of inspired oxygen.
a
Nasal CPAP, noninvasive positive pressure ventilation, high-flow nasal cannula.