Table 2.
Frequency of outcomes in infants with RDS, GA 30–36 weeks, and BW > 2 kg by surfactant exposure.
| Outcome | Surfactant (N = 25,278) | No surfactant (N = 29,686) | p value |
|---|---|---|---|
| Mortality, % | 0.4 | 0.1 | <0.001 |
| Air leaka, % | 8.9 | 4.8 | <0.001 |
| Pulmonary hemorrhage, % | 0.3 | 0.1 | <0.001 |
| Any mechanical ventilation, % | 52 | 9 | <0.001 |
| Total ventilator days, median (5–95th percentile) | 1 (0–6) | 0 (0–2) | <0.001 |
| BPD, % | 1.2 | 0.5 | <0.001 |
BPD bronchopulmonary dysplasia.
a
Air leak includes pneumothorax or pulmonary interstitial emphysema.