Fig 1. Time course of human lymphocyte reconstitution in peripheral blood of EBV-infected hu-NOG mice.
Following inoculation with EBV, the percentages of human CD45+, CD4+, CD8+, and CD19+ cells among the peripheral blood mononuclear cells were measured weekly. Upon EBV infection, the percentage of human CD8+ T cells increased rapidly, and the ratio of CD4+ cells to CD8+ cells decreased to below 1. Values represent mean ± standard error.