Table 3.

Multivariate Cox proportional hazards analysis for clinical outcomes according to the resistant hypertension definition

	aTRHprior HR [95% CI]	C‐index	P‐value	aTRHupdated HR [95% CI]	C‐index	P‐value
HF hospitalization	3.178 [1.040‐9.707]	0.853	.042	3.376 [1.134‐10.05]	0.870	.029
Stroke (non‐fatal)	2.393 [0.603‐9.505]	0.839	.215	1.767 [0.446‐7.009]	0.836	.418
MI (non‐fatal)	3.226 [0.567‐18.37]	0.824	.187	2.332 [0.410‐13.28]	0.821	.340
Renal event	1.537 [1.049‐2.252]	0.880	.028	1.493 [1.044‐2.135]	0.879	.028
Non‐fatal CVE	2.651 [1.189‐5.909]	0.796	.017	2.314 [1.058‐5.063]	0.802	.036
CV death	3.735 [0.284‐49.11]	0.976	.316	3.136 [0.233‐42.21]	0.975	.389
MACE	2.735 [1.355‐5.521]	0.798	.005	2.418 [1.182‐4.947]	0.804	.016

Adjusted for age, sex, diabetes, estimated glomerular filtration rate, and current smoking.

Abbreviations: CI, confidence interval; C‐index, Harrell's concordance index; HR, hazard ratio. Other abbreviations are defined in Tables 1 and 2.