TABLE 3.
Effect of adrenal artery ablation on biochemical improvement in PA patients
Variable | Biochemical improvement | P value | |||||
---|---|---|---|---|---|---|---|
Complete (n = 9, [25.0%]) | Partial (n = 13, [36.1%]) | Absent (n = 14, [38.9%]) | Overall | Complete vs Partial | Complete vs Absent | Partial vs Absent | |
Pre‐ablation | |||||||
Serum potassium—mmol/L | 4.11 ± 0.33 | 3.29 ± 0.68 | 3.54 ± 0.52 | .006 | .004 | .013 | .548 |
Plasma aldosterone in supine position—ng/dL | 20.75 ± 4.03 | 17.36 ± 2.11 | 19.07 ± 4.50 | .165 | .126 | .647 | .436 |
Plasma renin activity in supine position—ng/mL/h | 0.69 [0.64, 0.73] | 0.46 [0.10, 0.57] | 0.54 [0.10, 0.82] | .085 | NA | NA | NA |
Plasma aldosterone‐to‐renin ratio | 34.00 [25.25, 35.75] | 38.00 [31.00, 120.00] | 37.00 [25.25, 125.00] | .622 | NA | NA | NA |
Post‐ablation | |||||||
Serum potassium—mmol/L | 4.22 ± 0.67 | 4.08 ± 0.67 | 4.00 ± 0.41 | .681 | .885 | .656 | .927 |
Plasma aldosterone in supine position—ng/dL | 15.44 ± 5.05 | 17.50 ± 3.92 | 18.15 ± 4.76 | .388 | .580 | .433 | .925 |
Plasma renin activity in supine position—ng/mL/h | 1.01 [0.11, 2.88] | 1.65 [0.29, 3.86] | 0.10 [0.10, 1.09] | .048 | 1.000 | .469 | .045 |
Plasma aldosterone‐to‐renin ratio | 13.00 [6.50, 19.50] | 11.50 [5.00, 66.75] | 90.00 [17.00, 210.00] | .035 | 1.000 | .265 | .037 |
Pre‐and Post‐ablation Change | |||||||
Serum potassium—mmol/L | −0.34 ± 0.34 | −0.66 ± 1.05 | −0.16 ± 1.28 | .485 | .604 | .879 | .545 |
Plasma aldosterone in supine position—ng/dL | 4.75 ± 5.75 | 0.40 ± 5.15 | 0.92 ± 6.13 | .239 | .250 | .343 | .973 |
Plasma renin activity in supine position—ng/mL/h | −0.19 [−2.61, 0.59] | −1.01 [−3.84, −0.05] | 0.00 [−0.54, 0.39] | .072 | NA | NA | NA |
Plasma aldosterone‐to‐renin ratio | 14.00 [9.25, 17.50] | 30.50 [12.25, 60.40] | 28.00 [18.50, 48.50] | .085 | NA | NA | NA |
Data are mean ± SD, or median with interquartile range.
Abbreviation: SD, standard deviation.