Table 1.
Demographic, clinical, and routine biochemical characteristics in patients with diabetic and non‐diabetic CKD
| Parameter | Group | p | |
|---|---|---|---|
| Diabetic CKD | Non‐diabetic CKD | ||
| Ν | 48 | 48 | ‐ |
| Age (years) | 69.44 ± 9.73 | 68.35 ± 10.52 | .602 |
| Male (n, %) | 29 (60.4%) | 29 (60,4%) | 1.000 |
| Weight (kg) | 82.73 ± 17.33 | 84.21 ± 16.92 | .673 |
| BMI (m2) | 29.89 ± 6.49 | 29.45 ± 6.14 | .733 |
| Active smoking (n, %) | 12 (25.0%) | 9 (18.8%) | .459 |
| Hypertension (n, %) | 47 (97.9%) | 47 (97.9%) | 1.000 |
| Coronary heart disease (n, %) | 10 (20.8%) | 7 (14.9%) | .450 |
| Stroke (n, %) | 4 (8.3%) | 2 (4.2%) | .677 |
| Peripheral vascular disease (n, %) | 5 (10.4%) | 8 (16.7%) | .371 |
| Heart failure (n, %) | 1 (2.1%) | 3 (6.3%) | .617 |
| Dyslipidemia (n, %) | 39 (81.3%) | 30 (62.5%) | .041 |
| Antihypertensive (any) (n, %) | 47 (97.9%) | 47 (97.9%) | 1.000 |
| ACEI or ARB (n, %) | 36 (75.0%) | 26 (54.2%) | .033 |
| Diuretics (n, %) | 33 (68.8%) | 26 (54.2%) | .142 |
| CCB (n, %) | 38 (79.2%) | 33 (68.8%) | .352 |
| Β–blocker (n, %) | 28 (58.3%) | 24 (50.0%) | .413 |
| Statin (n, %) | 37 (77.1%) | 29 (60.4%) | .078 |
| Erythropoietin (n, %) | 2 (4.2%) | 3 (6.3%) | .646 |
| Insulin (n, %) | 22 (45.8%) | 0 (0%) | <.001 |
| Oral hypoglycemic agents (n, %) | 40 (83.3%) | 0 (0%) | <.001 |
| Hemoglobin (gr/dl) | 13.25 ± 1.46 | 13.32 ± 1.50 | .810 |
| HbA1c (%) | 7.02 ± 0.68 | 5.56 ± 0.43 | <.001 |
| Glucose (mg/dl) | 140.88 ± 40.46 | 89.65 ± 11.11 | <.001 |
| eGFR (ml/min/1.73 m2) | 46.69 ± 18.63 | 46.78 ± 17.85 | .981 |
| 24‐h Urine albumin (mg/24 h) | 185.75 [1203.12] | 178.95 [554.73] | .235 |
| 24‐h Urine sodium (mmol/24 h) | 144.17 ± 54.19 | 128.50 ± 57.49 | .173 |
| Uric acid (mg %) | 6.58 ± 1.72 | 6.34 ± 1.35 | .450 |
| Potassium (mEq/L) | 4.72 ± 0.45 | 4.56 ± 0.37 | .071 |
| Sodium (mEq/L) | 138.58 ± 2.81 | 138.79 ± 2.55 | .705 |
| Calcium (mg/dl) | 9.29 ± 0.75 | 9.48 ± 0.43 | .126 |
| Parathormone (pg/ml) | 57.70 [57.70] | 62.45 [34.85] | .892 |
| 24‐h brachial SBP | 132.13 ± 10.71 | 124.16 ± 11.45 | .001 |
| 24‐h brachial DBP | 75.00 ± 8.43 | 74.62 ± 6.86 | .809 |
| 24‐h heart rate | 69 ± 9 | 64 ± 9 | .024 |
| Antihypertensive (any) (n, %) | 47 (97.9%) | 47 (97.9%) | 1.000 |
| ACEI or ARB (n, %) | 36 (75.0%) | 26 (54.2%) | .033 |
| Diuretics (n, %) | 33 (68.8%) | 26 (54.2%) | .142 |
| CCB (n, %) | 38 (79.2%) | 33 (68.8%) | .352 |
| Β‐blocker (n, %) | 28 (58.3%) | 24 (50.0%) | .413 |
| Statin (n, %) | 37 (77.1%) | 29 (60.4%) | .078 |
| Erythropoietin (n, %) | 2 (4.2%) | 3 (6.3%) | .646 |
| Insulin (n, %) | 22 (45.8%) | 0 (0%) | <.001 |
| Oral hypoglycemic agents (n, %) | 40 (83.3%) | 0 (0%) | <.001 |
Statistically significant P values are marked with bold.
Abbreviations: ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, Body mass index; COPD, Chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein.