Table 1.
Demographic characteristics and clinical parameters of study population
| Controls (n = 55) | HT (n = 60) | DM + HT (n = 50) | P | |
|---|---|---|---|---|
| Age (y) | 51 ± 7 | 54 ± 8 | 56 ± 8 a | .004 |
| Female (%) | 26 (48) | 28 (47) | 24 (48) | .990 |
| BMI (kg/m2) | 26.2 ± 2.0 | 27.1 ± 2.2 | 27.4 ± 2.4 b | .015 |
| Heart rate (beats/min) | 70 ± 8 | 73 ± 9 | 75 ± 9 b | .013 |
| SBP (mm Hg) | 128 ± 9 | 147 ± 11 a | 145 ± 10 a | <.001 |
| DBP (mm Hg) | 72 ± 8 | 93 ± 9 a | 90 ± 8 a | <.001 |
| Antihypertensive therapy (%) | – | 19 (32) | 29 (58) | – |
| Antidiabetic therapy (%) | – | – | 28 (56) | – |
| Fasting glucose level (mmol/L) | 5.3 ± 0.7 | 5.1 ± 0.9 | 6.7 ± 1.2 a , c | <.001 |
| HbA1c (%) | 5.1 ± 0.7 | 5.3 ± 0.8 | 7.0 ± 1.0 a , c | <.001 |
| Triglycerides (mmol/L) | 1.6 ± 0.4 | 1.8 ± 0.5 | 2.4 ± 0.5 a , c | <.001 |
| Total cholesterol (mmol/L) | 5.0 ± 0.9 | 5.3 ± 1.0 | 6.1 ± 0.9 a , c | <.001 |
| Serum creatinine (umol/L) | 80 ± 10 | 83 ± 12 | 89 ± 11 a | .041 |
Abbreviations: BMI, body mass index; BP, blood pressure; DBP, diastolic blood pressure; DM, type 2 diabetes mellitus; HbA1c, glycosylated hemoglobin; HT, arterial hypertension; SBP, systolic blood pressure.
a
P < .01 vs controls.
b
P < .05 vs controls.
c
P < .01 vs HT.