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. 2020 Aug 9;22(8):1458–1465. doi: 10.1111/jch.13959

TABLE 1.

Characteristics of participants by eGFR values

Variable Total (n = 147) eGFR (mL/min per 1.73 m2)
<60 (n = 73) ≥60 (n = 74) P‐value
Age, years 72.8 ± 8.3 73.0 ± 9.3 72.8 ± 7.3 .88
Women, n (%) 58 (39.5) 26 (35.6) 32 (43.2) .34
Current smoker, n (%) 26 (17.7) 11 (15.1) 15 (20.2) .41
Current drinker, n (%) 74 (50.3) 34 (46.6) 40 (54.1) .37
BMI, kg/m2 24.2 ± 3.5 24.7 ± 3.8 23.7 ± 3.2 .11
SBP, mmHg 133.1 ± 14.2 133.0 ± 14.6 133.2 ± 13.9 .89
DBP, mmHg 74.2 ± 11.0 74.5 ± 12.6 74.0 ± 9.2 .80
Plasma glucose, mg/dL 130.6 ± 32.9 136.6 ± 40.0 126.0 ± 25.6 .09
Hemoglobin, g/dL 13.3 ± 1.5 12.9 ± 1.7 13.6 ± 1.2 .019
HbA1c, % 6.0 ± 0.6 6.2 ± 0.8 5.9 ± 0.4 .038
LDL cholesterol, mg/dL 104.0 ± 23.6 104.5 ± 24.5 103.5 ± 22.7 .80
HDL cholesterol, mg/dL 60.7 ± 16.2 58.3 ± 14.2 63.1 ± 17.8 .08
LDL/HDL 1.8 ± 0.6 1.9 ± 0.6 1.7 ± 0.6 .23
Triglycerides, mg/dL 155.6 ± 109.2 165.4 ± 135.2 146.0 ± 75.2 0.28
Estimated 24‐h urinary Na excretion, mEq/d 164.9 ± 43.0 166.3 ± 45.3 164.0 ± 41.6 .77
BNP, pg/mL 29.1 (16.4‐51.9) 34.3 (17.5‐62.8) 27.7 (13.1‐45.3) .03
UACR ≥ 30 mg/g Cr, n (%) 62 (42.2) 40 (54.8) 22 (29.7) .002
Urinary vanin‐1, ng/mg Cr 2.0 ± 3.9 2.9 ± 4.9 1.1 ± 1.9 .005
Urinary NGAL, ng/mg Cr 13.0 ± 12.0 13.9 ± 13.0 12.2 ± 10.9 .38
Urinary KIM‐1, ng/mg Cr 0.9 ± 1.3 1.0 ± 1.3 0.9 ± 1.3 .45

All results are presented as mean ± SD, median (interquartile range), or n (%).

Abbreviations: BMI, body mass index; BNP, B‐type natriuretic peptide; Cr, creatinine; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high‐density lipoprotein; KIM‐1, kidney injury molecule‐1; LDL, low‐density lipoprotein; NGAL, neutrophil gelatinase‐associated lipocalin; SBP, systolic blood pressure; UACR, urinary albumin‐to‐creatinine ratio.