TABLE 1.
Characteristics of participants by eGFR values
Variable | Total (n = 147) | eGFR (mL/min per 1.73 m2) | ||
---|---|---|---|---|
<60 (n = 73) | ≥60 (n = 74) | P‐value | ||
Age, years | 72.8 ± 8.3 | 73.0 ± 9.3 | 72.8 ± 7.3 | .88 |
Women, n (%) | 58 (39.5) | 26 (35.6) | 32 (43.2) | .34 |
Current smoker, n (%) | 26 (17.7) | 11 (15.1) | 15 (20.2) | .41 |
Current drinker, n (%) | 74 (50.3) | 34 (46.6) | 40 (54.1) | .37 |
BMI, kg/m2 | 24.2 ± 3.5 | 24.7 ± 3.8 | 23.7 ± 3.2 | .11 |
SBP, mmHg | 133.1 ± 14.2 | 133.0 ± 14.6 | 133.2 ± 13.9 | .89 |
DBP, mmHg | 74.2 ± 11.0 | 74.5 ± 12.6 | 74.0 ± 9.2 | .80 |
Plasma glucose, mg/dL | 130.6 ± 32.9 | 136.6 ± 40.0 | 126.0 ± 25.6 | .09 |
Hemoglobin, g/dL | 13.3 ± 1.5 | 12.9 ± 1.7 | 13.6 ± 1.2 | .019 |
HbA1c, % | 6.0 ± 0.6 | 6.2 ± 0.8 | 5.9 ± 0.4 | .038 |
LDL cholesterol, mg/dL | 104.0 ± 23.6 | 104.5 ± 24.5 | 103.5 ± 22.7 | .80 |
HDL cholesterol, mg/dL | 60.7 ± 16.2 | 58.3 ± 14.2 | 63.1 ± 17.8 | .08 |
LDL/HDL | 1.8 ± 0.6 | 1.9 ± 0.6 | 1.7 ± 0.6 | .23 |
Triglycerides, mg/dL | 155.6 ± 109.2 | 165.4 ± 135.2 | 146.0 ± 75.2 | 0.28 |
Estimated 24‐h urinary Na excretion, mEq/d | 164.9 ± 43.0 | 166.3 ± 45.3 | 164.0 ± 41.6 | .77 |
BNP, pg/mL | 29.1 (16.4‐51.9) | 34.3 (17.5‐62.8) | 27.7 (13.1‐45.3) | .03 |
UACR ≥ 30 mg/g Cr, n (%) | 62 (42.2) | 40 (54.8) | 22 (29.7) | .002 |
Urinary vanin‐1, ng/mg Cr | 2.0 ± 3.9 | 2.9 ± 4.9 | 1.1 ± 1.9 | .005 |
Urinary NGAL, ng/mg Cr | 13.0 ± 12.0 | 13.9 ± 13.0 | 12.2 ± 10.9 | .38 |
Urinary KIM‐1, ng/mg Cr | 0.9 ± 1.3 | 1.0 ± 1.3 | 0.9 ± 1.3 | .45 |
All results are presented as mean ± SD, median (interquartile range), or n (%).
Abbreviations: BMI, body mass index; BNP, B‐type natriuretic peptide; Cr, creatinine; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high‐density lipoprotein; KIM‐1, kidney injury molecule‐1; LDL, low‐density lipoprotein; NGAL, neutrophil gelatinase‐associated lipocalin; SBP, systolic blood pressure; UACR, urinary albumin‐to‐creatinine ratio.