Baseline characteristics of MC and non‐MC clusters stratified by sex. MC and non‐MC clusters consisted of 3726 individuals with grade 2 hypertension from FINRISK 1997, 2002, and 2007 cohorts. BMI, body‐mass index (kg/m2); eGFR, estimated glomerular filtration rate (mL/min/1.73 m2); Glucose, standardized Z‐score of either glycated hemoglobin or fasting glucose; logCRP, natural logarithm of C‐reactive protein concentration (mg/L); MAP, mean arterial pressure (mm Hg); MC, the metabolically challenged cluster with higher blood glucose and BMI; non‐HDLc, non‐high‐density lipoprotein cholesterol (mmol/L); non‐MC, the non‐metabolically challenged cluster with lower blood glucose and BMI; PP, pulse pressure (mm Hg); rAlcohol, rank‐normalized alcohol