TABLE 5.
The association between dispensed drugs and the risk of mortality in patients with atrial fibrillation a
| Men | Women | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |||
| All medication | 1.29 | 1.21 | 1.37 | 1.16 | 1.08 | 1.25 |
| a. Loop diuretics | 1.54 | 1.45 | 1.64 | 1.34 | 1.27 | 1.41 |
| b. Thiazides | 0.99 | 0.91 | 1.08 | 0.97 | 0.91 | 1.04 |
| c. Potassium‐saving agents | 1.34 | 1.18 | 1.53 | 1.08 | 0.99 | 1.19 |
| d. Beta‐1‐selective beta‐blockers | 0.94 | 0.90 | 0.98 | 0.94 | 0.91 | 0.98 |
| e. Non‐selective beta‐blockers | 0.86 | 0.79 | 0.94 | 0.85 | 0.79 | 0.92 |
| f. Heart‐active calcium channel blockers | 1.17 | 1.01 | 1.34 | 0.99 | 0.88 | 1.13 |
| g. Vessel‐active calcium channel blockers | 1.00 | 0.94 | 1.06 | 1.00 | 0.94 | 1.06 |
| h. ACE inhibitors | 1.17 | 1.12 | 1.23 | 1.18 | 1.12 | 1.25 |
| i. ARBs | 0.97 | 0.90 | 1.04 | 0.95 | 0.88 | 1.02 |
| j. Statins | 0.87 | 0.82 | 0.92 | 0.81 | 0.76 | 0.86 |
In the full model, we adjusted for age, region of Sweden, immigrant status, socioeconomic factors, comorbidities, and all drug classes.
Abbreviations: ARBs, angiotensin receptor blocking agents; HR, hazards ratios; CI, confidence intervals.
a
Full adjusted model.
Bold values are statistically significant.