Table 1.
Patient characteristics
|
Age < 60 (N = 970) |
Age 60‐79 (N = 3252) | Age ≥ 80 (N = 887) | P | |
|---|---|---|---|---|
| Age, y | 51.0 ± 6.6 | 69.8 ± 5.4 | 84.2 ± 3.5 | <.001 |
| Men, % | 61.4 | 51.9 | 44.0 | <.001 |
| Body mass index, kg/m2 | 26.5 ± 4.8 | 24.4 ± 3.6 | 23.7 ± 3.6 | <.001 |
| Diabetes, glucose tolerance disorder, % | 27.3 | 34.4 | 30.2 | <.001 |
| Dyslipidemia, % | 51.4 | 59.7 | 53.9 | <.001 |
| High‐normal normotension and grade I‐III hypertension, % | 78.6 | 83.0 | 91.0 | <.001 |
| Current smoker, % | 17.0 | 8.4 | 3.2 | <.001 |
| Renal disease, % | 7.0 | 19.0 | 37.6 | <.001 |
| Past history of cardiovascular disease, % | 17.0 | 24.1 | 29.2 | <.001 |
| Atrial fibrillation, % | 5.1 | 9.4 | 13.3 | <.001 |
| Metabolic syndrome, % | 12.9 | 10.5 | 7.9 | .002 |
| Chronic obstructive pulmonary disease, % | 0.9 | 1.7 | 3.3 | .001 |
| Sleep apnea syndrome, % | 9.6 | 4.2 | 1.6 | <.001 |
| Cardio‐ankle vascular index | 7.6 ± 1.1 | 8.9 ± 1.2 | 9.8 ± 1.3 | <.001 |
| Systolic blood pressure (mm Hg) | 131.7 ± 15.3 | 133.3 ± 16.2 | 136.0 ± 18.9 | <.001 |
| Diastolic blood pressure (mm Hg) | 82.3 ± 10.5 | 76.4 ± 9.9 | 72.3 ± 10.8 | <.001 |
| Mean pressure (mm Hg) | 98.8 ± 11.3 | 95.4 ± 10.7 | 93.6 ± 11.9 | <.001 |
| Pulse rate (bpm) (N = 5055) | 74.0 ± 12.2 | 71.5 ± 12.1 | 74.2 ± 13.6 | <.001 |
| Total cholesterol (N = 4644) | 199.2 ± 36.5 | 189.7 ± 32.9 | 180.2 ± 31.6 | <.001 |
| LDL cholesterol (N = 3696) | 115.4 ± 31.5 | 106.6 ± 27.5 | 97.6 ± 26.7 | <.001 |
| HDL cholesterol (N = 4541) | 56.8 ± 16.0 | 58.8 ± 16.4 | 56.5 ± 15.6 | <.001 |
| Triglyceride (N = 4972) | 148.6 ± 103.0 | 123.8 ± 73.6 | 113.3 ± 55.2 | <.001 |
| Glucose (N = 4923) | 111.2 ± 28.5 | 112.6 ± 32.1 | 110.4 ± 32.9 | .141 |
| HbA1c (N = 4650) | 6.1 ± 0.9 | 6.2 ± 0.8 | 6.1 ± 0.7 | <.001 |
| Uric acid (N = 4935) | 5.9 ± 1.4 | 5.5 ± 1.9 | 5.4 ± 1.4 | <.001 |
Abbreviations: HDL, high‐density lipoprotein; LDL, low‐density lipoprotein.