Molecular mechanisms of blood pressure control in subjects with Down syndrome ACE, angiotensin‐converting enzyme; Bk, bradykinin; B2, bradykinin receptor B2; NO, nitric oxide; NOS, nitric oxide syntase; L‐Arg, L‐arginine. Yellow square: genes in the chromosome 21; Blue circle: their action affect blood pressure and atherosclerosis; Red line: inhibition; Black line: activation; Dashed line: relation