Table 2.

PICOS approach to study eligibility

	Inclusion	Exclusion
Population (P)	A general population of all individuals without reference to any specific characteristic, such as age, sex, or disease condition.	Animal studies
		Vitro studies
Intervention (I)	Any kinds of low‐sodium salt interventions (including exposure to low‐sodium salt)	Other salt reduction interventions and low‐sodium diet without low‐sodium salt; Using herb, vitamins, yeast as low‐sodium salt, which is not food additive that tasted like salt; Taking sodium or potassium supplementation/tablet; Using other salt without sodium reduced, such as sea salt and iodation salt Intervention shorter than 7 d
Comparators (C)	Placebo, regular salt, no intervention, and other interventions.
Outcomes (O)	Health‐related outcomes
	Adverse effects
	Acceptability of low‐sodium salt
Study design	Randomized controlled trials (RCTs), non‐randomized controlled trials, qualitative studies, case study, and unpublished and ongoing studies	Review papers, letters/comments, and editorials