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. 2019 Apr 13;21(5):627–634. doi: 10.1111/jch.13531

Table 2.

Unmatched clinical outcomes and efficacy parameters after 3 y, as documented in patients' EMR

  Diuretics Beta blockers RAS blockers CCB
N 13 808 20 538 35 783 9159
Three‐y outcomes (30 until 1095 d after index); before propensity matching
First stroke (I63) (%) 0.7 1.3 0.8 1.3
Any cerebrovascular outcome (I60‐I69) (%) 2.5 3.9 2.4 4.1
Myocardial infarction (I21) (%) 0.2 0.9 0.2 0.3
Any ischemic heart disease (I20‐I25) (%) 2.8 6.6 2.6 4.1
Chronic kidney disease (N18, I12, I13) (%) 2.3 2.4 2.6 3.0
Any of these CV outcomes (%) 5.2 9.5 5.4 7.6
Efficacy parameters
LDL cholesterol, mg/dL 114.7 108.1 109.24 110.32
  −2.9 −4.4 −6.1 −3.3
Uncontrolled BP values, any episode (%) 42.9 45.9 28.7 35.8
Man systolic BP, most recent value, mm Hg 128.7 128.1 128.9 132.2
±SD 15.4 16.7 15.1 16.2
Difference to baseline −4.9 −3.6 −5.8 −4.8
Mean diastolic BP, most recent value, mm Hg 77.1 76.0 77.2 77.7
±SD 10.5 10.6 10.0 10.5
Difference to baseline −3.1 −2.2 −3.8 −3.2
Heart rate/min 78.1 72.7 77.3 77.1
Difference to baseline −2.2 −4.9 −1.5 −2.1

Mean C‐reactive protein,

most recent value, mg/L, mean

8.3 8.5 9.3 6.8
Difference to baseline −1.2 0.8 0.4 −0.1