Table 4.
Univariate analysis and multivariate analysis for major cardiovascular events
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| Old age (>60 y) | 3.13 | 2.59‐3.77 | <0.001 | 2.21 | 1.77‐2.78 | <0.001 |
| Male gender | 0.56 | 0.48‐0.65 | <0.001 | 0.82 | 0.69‐0.99 | 0.036 |
| Hypertension | 1.83 | 1.57‐2.14 | <0.001 | 1.29 | 1.08‐1.54 | 0.006 |
| Diabetes mellitus | 1.99 | 1.71‐2.31 | <0.001 | 1.38 | 1.16‐1.65 | <0.001 |
| Dyslipidemia | 0.77 | 0.59‐0.99 | 0.045 | 0.83 | 0.63‐1.10 | 0.197 |
| Body mass index (>24 kg/m2) | 0.62 | 0.53‐0.73 | <0.001 | 0.80 | 0.68‐0.95 | <0.001 |
| LV dysfunction (EF < 50%) | 1.80 | 1.55‐2.09 | <0.001 | 1.37 | 1.60‐1.63 | <0.001 |
| Renal failure (Cr > 2.0 mg/dL) | 4.40 | 3.62‐5.34 | <0.001 | 2.37 | 1.86‐3.03 | <0.001 |
| Current smoking | 0.57 | 0.49‐0.68 | <0.001 | 1.08 | 0.88‐1.32 | 0.466 |
| Multivessel disease & LM disease | 1.53 | 1.31‐1.79 | <0.001 | 1.22 | 1.03‐1.43 | 0.021 |
| STEMI vs NSTEMI | 0.60 | 0.51‐0.70 | <0.001 | 0.69 | 0.59‐0.83 | <0.001 |
| Killip class >2 | 2.57 | 2.16‐3.06 | <0.001 | 1.48 | 1.21‐1.82 | <0.001 |
| Medication use | ||||||
| beta‐blocker | 0.65 | 0.54‐0.77 | <0.001 | 0.83 | 0.67‐1.02 | 0.078 |
| ACEI or ARB | 0.70 | 0.59‐0.83 | <0.001 | 0.95 | 0.78‐1.16 | 0.588 |
| Statin | 0.38 | 0.31‐0.47 | <0.001 | 0.66 | 0.51‐0.86 | 0.002 |
| PP group (mm Hg) | ||||||
| >‐20 | 2.34 | 1.24‐4.40 | 0.008 | 2.14 | 1.06‐4.35 | 0.035 |
| 21‐30 | 1.11 | 0.86‐1.44 | 0.419 | 1.20 | 0.91‐1.59 | 0.195 |
| 31‐40 | Reference | Reference | ||||
| 41‐50 | 1.08 | 0.89‐1.31 | 0.415 | 1.02 | 0.83‐1.25 | 0.887 |
| 51‐60 | 1.41 | 1.13‐1.76 | 0.002 | 0.08 | 0.85‐1.38 | 0.521 |
| 61‐70 | 1.50 | 1.09‐2.07 | 0.014 | 0.87 | 0.60‐1.27 | 0.475 |
| 71‐< | 2.72 | 1.95‐3.80 | <0.001 | 1.21 | 0.83‐1.77 | 0.328 |
Abbreviations: CI, confidence interval; EF, ejection fraction; HR, hazard ratio; LM, left main; (N)STEMI, (non)‐ST elevation myocardial infarction; PP, pulse pressure; RAAS, renin‐aldosterone‐angiotensin system.