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. 2019 Apr 23;21(6):774–785. doi: 10.1111/jch.13534

Table 4.

Univariate analysis and multivariate analysis for major cardiovascular events

  Univariate analysis Multivariate analysis
HR 95% CI P Value HR 95% CI P Value
Old age (>60 y) 3.13 2.59‐3.77 <0.001 2.21 1.77‐2.78 <0.001
Male gender 0.56 0.48‐0.65 <0.001 0.82 0.69‐0.99 0.036
Hypertension 1.83 1.57‐2.14 <0.001 1.29 1.08‐1.54 0.006
Diabetes mellitus 1.99 1.71‐2.31 <0.001 1.38 1.16‐1.65 <0.001
Dyslipidemia 0.77 0.59‐0.99 0.045 0.83 0.63‐1.10 0.197
Body mass index (>24 kg/m2) 0.62 0.53‐0.73 <0.001 0.80 0.68‐0.95 <0.001
LV dysfunction (EF < 50%) 1.80 1.55‐2.09 <0.001 1.37 1.60‐1.63 <0.001
Renal failure (Cr > 2.0 mg/dL) 4.40 3.62‐5.34 <0.001 2.37 1.86‐3.03 <0.001
Current smoking 0.57 0.49‐0.68 <0.001 1.08 0.88‐1.32 0.466
Multivessel disease & LM disease 1.53 1.31‐1.79 <0.001 1.22 1.03‐1.43 0.021
STEMI vs NSTEMI 0.60 0.51‐0.70 <0.001 0.69 0.59‐0.83 <0.001
Killip class >2 2.57 2.16‐3.06 <0.001 1.48 1.21‐1.82 <0.001
Medication use
beta‐blocker 0.65 0.54‐0.77 <0.001 0.83 0.67‐1.02 0.078
ACEI or ARB 0.70 0.59‐0.83 <0.001 0.95 0.78‐1.16 0.588
Statin 0.38 0.31‐0.47 <0.001 0.66 0.51‐0.86 0.002
PP group (mm Hg)
>‐20 2.34 1.24‐4.40 0.008 2.14 1.06‐4.35 0.035
21‐30 1.11 0.86‐1.44 0.419 1.20 0.91‐1.59 0.195
31‐40 Reference     Reference    
41‐50 1.08 0.89‐1.31 0.415 1.02 0.83‐1.25 0.887
51‐60 1.41 1.13‐1.76 0.002 0.08 0.85‐1.38 0.521
61‐70 1.50 1.09‐2.07 0.014 0.87 0.60‐1.27 0.475
71‐< 2.72 1.95‐3.80 <0.001 1.21 0.83‐1.77 0.328

Abbreviations: CI, confidence interval; EF, ejection fraction; HR, hazard ratio; LM, left main; (N)STEMI, (non)‐ST elevation myocardial infarction; PP, pulse pressure; RAAS, renin‐aldosterone‐angiotensin system.