Table 6.
Association between pulse pressure at discharge and MACEs and cardiac death in patients with acute myocardial infarction
| Unadjusted HR (95% CI) | P‐Value | Adjusted HR (95% CI) | P‐Value | ||
|---|---|---|---|---|---|
| MACEs | PP (for every 10 mm Hg increase in PP up to 40 mm Hg) | 0.775 (0.610‐0.985) | 0.037 | 0.784 (0.620‐0.992) | 0.043 |
| PP (for every 10 mm Hg increase in PP ≥ 40 mm Hg) | 1.242 (1.157‐1.333) | <0.001 | 1.017 (0.942‐1.098) | 0.664 | |
| Cardiac death | PP (for every 10 mm Hg increase in PP up to 40 mm Hg) | 0.785 (0.605‐1.017) | 0.067 | 0.748 (0.577‐0.970) | 0.028 |
| PP (for every 10 mm Hg increase in PP ≥ 40 mm Hg) | 1.257 (1.166‐1.356) | <0.001 | 1.039 (0.955‐1.130) | 0.374 |
Abbreviations: CI, confidence interval; HR, hazard ratio; MACEs, major adverse cardiovascular events; PP, pulse pressure.
Analyses were adjusted for the following covariates: old age (>60 y); male sex; body mass index (>24 kg/m2); history of hypertension, diabetes, and dyslipidemia; renal failure (creatinine level > 2.0 mg/dL); left ventricular (LV) dysfunction, characterized by LV ejection fraction <50%; current smoking; multivessel disease or LM disease; STEMI vs NSTEMI, poor Killip classification, characterized by Killip ≥3; and medications (beta‐blocker, angiotensin‐converting enzyme inhibitor or angiotensin receptor blocker, statin).