Table 2.

Multivariate logistic regression of HTN or HHcy on CKD and its components

Risk factors	ORs	95% CI	P value
Crude model
CKD
HTN	4.515	4.004, 5.091	<.001
HHcy	4.869	4.080, 5.810	<.001
Reduced eGFR
HTN	8.554	7.449, 9.822	<.001
HHcy	11.269	8.916, 14.244	<.001
Albuminuria
HTN	3.366	2.930, 3.865	<.001
HHcy	2.824	2.356, 3.384	<.001
Multivariate adjusted model without multiplicative interaction term
CKD
HTN	1.787	1.562‐2.044	<.001
HHcy	2.985	2.472‐3.606	<.001
Reduced eGFR
HTN	1.818	1.499‐2.203	<.001
HHcy	6.573	5.075‐8.512	<.001
Albuminuria
HTN	1.959	1.659‐2.313	<.001
HHcy	1.880	1.527‐2.314	<.001
Multivariate adjusted model with multiplicative interaction term
CKD
HTN	1.594	1.363, 1.865	<.001
HHcy	2.371	1.772, 3.174	<.001
Reduced eGFR
HTN	1.512	1.166, 1.962	<.001
HHcy	5.180	3.391, 7.911	<.001
Albuminuria
HTN	1.844	1.532, 2.219	<.001
HHcy	1.590	1.137, 2.224	<.001

Abbreviations: BMI, body mass index; CI, confidence intervals; CKD, chronic kidney disease; DM, diabetes mellitus; eGFR, estimated glomerular filtration ratio; HDL‐C, high‐density lipoprotein cholesterol; HHcy, hyperhomocysteinemia; HTN, hypertension; PIR, poverty‐to‐income ratio; TC, total cholesterol; WC, waist circumference.

Crude model: no adjustment; multivariate adjusted model without multiplicative interaction term: adjusted by age, sex, race, education level, PIR, physical activity, drinking frequency, current smoking status, TC, HDL‐C, serum folate, vitamin B12, BMI, WC, and DM; multivariate adjusted model with multiplicative interaction term: adjusted by age, sex, race, education level, PIR, physical activity, drinking frequency, current smoking status, TC, HDL‐C, serum folate, vitamin B12, BMI, WC, DM, and interaction term of HTN and HHcy.