Table 3.
Hemodynamic parameters during HUTT
| Parameters | Baseline | 1‐y follow‐up | P value, difference mean (95% CI) |
|---|---|---|---|
| sBP (mm Hg) | |||
| supinea | 134.6 (12.6) | 122.8 (10.7) | <0.0001, −11.83 (−15.19 to −8.464) |
| during tilta | 140.7 (12.7) | 127.9 (11.6) | <0.0001, −12.81 (−16.4 to −9.224) |
| change (%)a | 4.6 (4.4) | 4.2 (4.2) | 0.5814 |
| dBP (mm Hg) | |||
| supinea | 91.6 (9.4) | 82.8 (8.7) | <0.0001, −8.822 (−11.4 to −6.246) |
| during tilta | 100.7 (10.1) | 90.9 (8.6) | <0.0001, −9.741 (−12.24 to −7.241) |
| change (%)a | 10 (5.3) | 10 (4.3) | 0.9799 |
| mBP (mm Hg) | |||
| supinea | 103.6 (10) | 94.4 (8.4) | <0.0001, −9.245 (−12.01 to −6.477) |
| during tilta | 112.6 (10.4) | 101.8 (8.8) | <0.0001, −10.74 (−13.48 to −7.993) |
| change (%)a | 8.8 (4.8) | 8 (4.2) | 0.3710 |
| HR (beats/min) | |||
| supineb | 72.4/13.8 | 67.9/11 | 0.0019, −3.629 (−6.423 to −0.8347) |
| during tilta | 83.8 (10.7) | 80.2 (11) | 0.0358, −3.57 (−6.893 to −0.2464) |
| change (%)a | 15 (8.4) | 15.9 (9.4) | 0.4713 |
| SI (ml/m2) | |||
| supinea | 40.6 (9.7) | 41.1 (9.4) | 0.6402, 0.4388 (−1.437 to 2.315) |
| during tilta | 29.9 (5.7) | 30.9 (5.8) | 0.0632, 1.054 (−0.0605 to 2.168) |
| change (%)a | −24.7 (12.3) | −23.3 (11.6) | 0.3628 |
| TPRI (dyn × sec/cm5) | |||
| supineb | 2839/1268 | 2722/1045 | 0.0937, −187.2 (−358 to −16.47) |
| during tilta | 3728 (902) | 3383 (813) | 0.0003, −345.1 (−525.1 to −165.2) |
| change (%)b | 26.4/26.3 | 24.5/29 | 0.1082 |
| CBFVm (cm/s) | |||
| supineb | 67.5/13.1 | 67/12.3 | 0.7564, −0.4512 (−3.369 to 2.466) |
| during tiltb | 61.4/12.8 | 59.6/11.2 | 0.1881, −1.759 (−4.412 to 0.8947) |
| change (%)b | −8.8/6.3 | −10.8/4.8 | 0.0852 |
CBFVm, mean cerebral blood flow velocity; CI, confidence interval; dBP, diastolic blood pressure; HR, heart rate; HUTT, head‐up tilt test; mBP, mean blood pressure; sBP, systolic blood pressure; SI, stroke index; TPRI, total peripheral resistance index. n = 42 for CBFVm, n = 49 for the rest of the parameters.
a
Paired t test: data expressed as mean (SD).
b
Wilcoxon matched‐pairs signed‐ranks test: data expressed as median/interquartile range.