TABLE 6.

Per-protocol analysis of the associations between fecal bacteria, fecal metabolites, and metabolic outcomes at the 12-wk follow-up in adults who consumed a daily isocaloric meal with avocado¹

		Roseburia		Ruminococcus		Lachnospira		Alistipes 2		Faecalibacterium
	n	r	P	ρ	P	r	P	r	P	r	P
Acetate, μmol/g DM feces	54	0.13	0.36	0.02	0.87	−0.06	0.65	−0.26	0.06	0.24	0.08
Cholic acid, μmol/g dry feces,	40	−0.29	0.07	−0.05	0.74	−0.29	0.07	−0.35	0.03	0.04	0.79
Chenodeoxycholic acid, μmol/g dry feces	36	−0.10	0.56	−0.11	0.54	−0.23	0.18	−0.20	0.23	0.13	0.45
Lithocholic acid, μmol/g dry feces	45	0.05	0.72	−0.11	0.48	0.12	0.43	0.06	0.70	−0.06	0.69
Deoxycholic acid, μmol/1 g dry feces	43	−0.19	0.23	−0.16	0.31	−0.12	0.46	−0.20	0.20	−0.07	0.64
Plasma glucose AUC, mmol/L × 120 min	46	−0.09	0.55	−0.05	0.76	−0.09	0.56	−0.16	0.30	−0.08	0.60
Plasma insulin AUC, pmol/L × 120 min	45	0.08	0.60	−0.27	0.08	−0.32	0.03	−0.13	0.38	−0.02	0.88
HOMA-IR	45	−0.02	0.91	−0.14	0.35	−0.08	0.61	−0.09	0.57	0.04	0.79
Matsuda index	44	−0.15	0.35	0.26	0.09	0.19	0.22	0.14	0.37	−0.05	0.77
Plasma TNF-ɑ pg/mL	50	−0.04	0.80	−0.02	0.92	−0.15	0.29	−0.09	0.53	0.00	0.98
Plasma CRP, μg/mL	49	0.13	0.37	−0.12	0.42	−0.17	0.23	0.22	0.13	0.15	0.32
Plasma IL-6, pg/mL	49	0.09	0.54	−0.03	0.83	−0.08	0.60	0.23	0.11	0.12	0.42
Visceral abdominal adiposity, g	53	−0.14	0.33	−0.27	0.05	−0.09	0.52	0.10	0.47	−0.12	0.38
Subcutaneous abdominal adiposity, g	53	−0.02	0.87	0.00	0.99	−0.10	0.48	0.26	0.06	0.03	0.84

¹Data were analyzed by Spearman or Pearson bivariate correlations. CRP, C-reactive protein; HOMA-IR, homeostatic model assessment of insulin resistance; IL-6, interleukin-6; TNF-ɑ, tumer necrosis factor ɑ; .

²Data were transformed prior to analysis.