. 2016 Jul 15;19(1):82–89. doi: 10.1111/jch.12873

Table 3.

Change From Baseline DBP and SBP as Measured by ABPM

ABPM Variable	Placebo (n=59)	AZL 2.5 mg (n=58)	AZL 5 mg (n=65)	AZL 10 mg (n=59)	AZL 20 mg (n=65)	AZL 40 mg (n=66)	OLM 20 mg (n=61)
Mean 24‐h DBP	−0.5±1.0	−5.9±1.0^a	−7.0±0.9^a	−7.3±1.0^a	−9.2±0.9a,b	−9.8±0.9a,b	−6.4±0.9^a
Mean daytime DBP while awake	−0.1±1.0	−6.1±1.0^a	−6.7±1.0^a	−7.5±1.0^a	−9.2±1.0a,b	−10.4±0.9^a,c	−6.5±1.0^a
Mean nighttime DBP while asleep	−0.5±1.1	−5.4±1.1^d	−7.1±1.1^a	−6.0±1.1^d	−8.0±1.1^a	−7.7±1.1^a	−5.7±1.1^d
Mean trough DBP	−0.5±1.3	−6.7±1.3^d	−6.8±1.2^a	−8.4±1.3^a	−7.2±1.2^a	−9.9±1.2a,b	−5.5±1.3^d
Mean 24‐h SBP	−0.1±1.5	−9.4±1.5^a	−11.3±1.4^a	−9.7±1.5^a	−14.9±1.4a,b	−15.3±1.4^a,d	−10.2±1.4^a
Mean daytime SBP while awake	0.4±1.5	−9.5±1.5^a	−11.0±1.5^a	−9.9±1.5^a	−14.8±1.5a,b	−16.3±1.4^a,c	−10.2±1.5^a
Mean nighttime SBP while asleep	−0.3±1.6	−8.8±1.6^a	−11.6±1.5^a	−8.5±1.6^a	−13.6±1.5^a	−11.5±1.5^a	−9.4±1.6^a
Mean trough SBP	−0.4±1.8	−10.7±1.8^a	−12.0±1.7^a	−11.2±1.8^a	−13.0±1.7^a	−13.3±1.7^a	−8.9±1.8^a

Abbreviations: ABPM, ambulatory blood pressure monitoring; AZL, azilsartan; DBP, diastolic blood pressure; OLM, olmesartan medoxomil; SBP, systolic blood pressure. All data are expressed as least squares mean±standard error (mm Hg) at week 8. ^a P<0.001 vs placebo. ^b P<0.05 vs OLM. ^c P<0.01 vs OLM. ^d P<0.01 vs placebo.