Table 2.
Commonly used oral antihypertensive drugs
| Class and drug | Biological half‐life, h | Daily dose, mg | No. of doses per d |
|---|---|---|---|
| Angiotensin‐converting enzyme inhibitor | |||
| Benazepril | 11 | 10–40 | 1 or 2 |
| Captopril | 1.9 | 50–150 | 2 |
| Enalapril | 11 | 2.5–40 | 1 or 2 |
| Lisinopril | 12 | 10–40 | 1 |
| Perindopril | 17 | 2–8 | 1 |
| Ramipril | 4 | 2.5–20 | 1 or 2 |
| Angiotensin receptor blocker | |||
| Candesartan | 9 | 4–32 | 1 |
| Irbesartan | 15 | 75–300 | 1 |
| Losartan | 2 | 25–100 | 1 or 2 |
| Olmesartan | 13 | 10–40 | 1 |
| Telmisartan | 24 | 20–80 | 1 |
| Valsartan | 6 | 80–320 | 1 |
| β‐Blocker | |||
| Atenolol | 7 | 25–100 | 1 |
| Bisoprolol | 12 | 2.5–10 | 1 |
| Metoprolol | 3–7 | 50–200 | 1 or 2 |
| Dihydropyridine calcium channel blocker | |||
| Amlodipine | 30–55 | 2.5–10 | 1 |
| Felodipine ER | 11–17 | 1.5–10 | 1 |
| Lacidipine | 13–19 | 2–4 | 1 |
| Lercanidipine | 8–10 | 10–20 | 1 |
| Nifedipine GITS | 2 | 20–80 | 1 |
| Nitrendipine | 8–24 | 10–40 | 1 or 2 |
| Thiazide diuretic | |||
| Chlorthalidone | 40 | 25–50 | 1 |
| Hydrochlorothiazide | 5.6–14.8 | 12.5–50 | 1 or 2 |
| Indapamide | 14–18 | 1.25–5 | 1 |
Abbreviations: ER, extended‐release; GITS, gastrointestinal therapeutic system.
The classes and drugs are listed alphabetically for the five classes of guideline‐recommended antihypertensive drugs. Data were obtained from Wikipedia (accessed July 18, 2017).