Table 3.
Multiple Regression Analyses With MCP‐1 as an Independent Variable
| Standard β (95% CI) | P Value | cIMT | P Value | |
|---|---|---|---|---|
| cfPWV | ||||
| Black men | ||||
| R²/adjusted R² | 0.260/0.161 | 0.101/– | ||
| bMAP | 0.401 (0.29–0.51) | .001 | 0.146 (0.02–0.27) | .24 |
| Age | 0.250 (0.13–0.37) | .039 | 0.100 (−0.03 to 0.23) | .45 |
| MCP‐1 | 0.001 (−0.11 to 0.11) | .99 | 0.107 (−0.02 to 0.23) | .39 |
| TNF‐α | 0.004 (−0.11 to 0.11) | .97 | −0.020 (−0.14 to 0.11) | .87 |
| VCAM‐1 | 0.011 (−0.09 to 0.12) | .92 | 0.053 (−0.07 to 0.17) | .66 |
| ROS | 0.093 (−0.02 to 0.21) | .39 | −0.079 (−0.19 to 0.04) | .51 |
| LDL‐C | −0.169 (−0.29 to −0.05) | .17 | 0.127 (−0.01 to 0.26) | .36 |
| Glucose | −0.108 (−0.22 to 0.01) | .34 | −0.111 (−0.24 to 0.01) | .38 |
| Waist circumference | −0.031 (−0.15 to 0.09) | .81 | −0.195 (−0.33 to −0.06) | .16 |
| White men | ||||
| R²/adjusted R² | 0.398/0.308 | 0.127/0.009 | ||
| bMAP | 0.511 (0.39–0.63) | <.001 | −0.015 (−0.15 to 0.12) | .91 |
| Age | 0.129 (0.02–0.24) | .24 | 0.131 (0.01–0.25) | .29 |
| MCP‐1 | 0.113 (−0.01 to 0.23) | .35 | −0.004 (−0.14 to 0.13) | .98 |
| TNF‐α | 0.076 (−0.03 to 0.18) | .48 | 0.081 (−0.04 to 0.21) | .51 |
| VCAM‐1 | −0.048 (−0.16 to 0.06) | .67 | −0.215 (−0.34 to −0.09) | .09 |
| ROS | −0.067 (−0.18 to 0.04) | .55 | −0.034 (−0.16 to 0.09) | .79 |
| LDL‐C | 0.029 (−0.08 to 0.13) | .78 | −0.028 (−0.15; 0.09) | .82 |
| Glucose | 0.117 (−0.82 to 1.1) | .28 | 0.036 (−1.08 to 1.11) | .77 |
| Waist circumference | 0.055 (−0.06 to 0.17) | .65 | −0.199 (−0.34 to −0.06) | .15 |
| Black women | ||||
| R²/adjusted R² | 0.273/0.184 | 0.238/0.151 | ||
| bMAP | 0.267 (0.16–0.38) | .016 | 0.309 (0.21–0.42) | .005 |
| Age | 0.396 (0.28–0.51) | .001 | 0.118 (0.01–0.23) | .29 |
| MCP‐1 | −0.138 (−0.24 to −0.03) | .19 | 0.248 (0.14–0.35) | .021 |
| TNF‐α | −0.122 (−0.23 to −0.02) | .25 | −0.051 (−0.16 to 0.05) | .63 |
| VCAM‐1 | −0.086 (−0.19 to 0.02) | .43 | 0.251 (0.14–0.36) | .022 |
| ROS | −0.0006 (−0.11 to 0.11) | .99 | 0.069 (−0.04 to 0.17) | .51 |
| LDL‐C | −0.072 (−0.18 to 0.04) | .51 | 0.079 (−0.03 to 0.19) | .46 |
| Glucose | −0.034 (−0.14 to 0.07) | .75 | −0.197 (−0.31 to −0.09) | .07 |
| Waist circumference | −0.241 (−0.35 to −0.13) | .036 | −0.152 (−0.26 to −0.04) | .18 |
| White women | ||||
| R²/adjusted R² | 0.134/0.059 | 0.054/– | ||
| bMAP | 0.328 (0.22–0.44) | .003 | 0.111 (−0.01 to 0.22) | .33 |
| Age | 0.171 (0.08–0.27) | .078 | 0.126 (0.03–0.23) | .21 |
| MCP‐1 | −0.009 (−0.11 to 0.09) | .93 | −0.012 (−0.11 to 0.09) | .91 |
| TNF‐α | −0.099 (−0.19 to −0.01) | .31 | 0.073 (−0.03 to 0.17) | .46 |
| VCAM‐1 | −0.028 (−0.12 to 0.07) | .77 | 0.141 (0.04–0.24) | .16 |
| ROS | −0.077 (−0.17 to 0.02) | .43 | 0.141 (0.04–0.24) | .17 |
| LDL‐C | −0.015 (−0.11 to 0.08) | .88 | 0.023 (−0.08 to 0.12) | .82 |
| Glucose | 0.116 (0.02–0.21) | .22 | 0.037 (−0.06 to 0.13) | .71 |
| Waist circumference | −0.086 (−0.21 to 0.03) | .46 | −0.127 (−0.25 to −0.01) | .29 |
Abbreviations: bMAP, brachial mean arterial pressure; cfPWV, carotid‐femoral pulse wave velocity; CI, confidence interval; cIMT, carotid intima‐media wall thickness; LDL‐C, low‐density lipoprotein cholesterol; MCP‐1, monocyte chemoattractant protein‐1; ROS, reactive oxygen species; TNF‐α, tumor necrosis factor α; VCAM‐1, vascular cell adhesion molecule‐1.
Bold values indicate P<.05.