Random‐effect meta‐analysis of the effects of renin‐angiotensin system (RAS) inhibitors vs calcium channel blockers (CCBs) on all‐cause mortality, myocardial infarction, stroke, heart failure, and composite outcome. The figure presents number of events, number of patients in the treatment and control groups, odds ratio (OR) and 95% confidence interval (CI) for each trial, overall OR estimate with 95% CI and P value for association test, P value for heterogeneity test, and between‐trial inconsistency (I
2) measures. ACEI/ARB indicates angiotensin‐converting enzyme inhibitor/angiotensin receptor blocker.