Table 4.

Comparison of blood pressure and number of HTMs in patients with unilateral and bilateral PA, before and after adrenalectomy and ARI, respectively

Unilateral	Prior to Surgery	1 to 2 y Post‐Op	3 to 4 y Post‐Op	5 to 6 y Post‐Op	P Value
SBP, mean±SD, mm Hg	161±18	145±20	144±18	135±10	<.001
DBP, mean±SD, mm Hg	96±12	88±10	90±12	90±11	.12
No. of HTMs, mean±SD	2.9±0.8	2.0±1.6	2.3±1.5	1.9±0.7	.01

Bilateral	Prior to ARI	1 to 2 y After ARI	3 to 4 y After ARI	5 to 6 y After ARI	P Value
SBP, mean±SD, mm Hg	152±23	147±18	143±19	138±17	.17
DBP, mean±SD, mm Hg	85±11	88±10	88±12	87±7	.70
No. of HTMs, mean±SD	1.8±1.2	2.1±1.3	2.0±1.0	2.0±1.1	.09

Abbreviations: ARI, aldosterone receptor inhibitor; DBP, diastolic blood pressure; SBP, systolic blood pressure; SD, standard deviation. A linear mixed effect model was used for the comparisons of blood pressure and number of hypertensive medications (HTMs; after diagnosis with adrenal venous sampling, these can include aldosterone inhibitors) prior to surgery and 1 to 2, 3 to 4, and 5 to 6 years after follow‐up. Two‐sided P value <.05 was considered statistically significant.