Table 2.
Changes in nocturnal BP parameters
| Variable | Morning administration (n = 23) | Bedtime administration (n = 23) | Comparison between groups | ||
|---|---|---|---|---|---|
| Change, mean (95% CI) | P value | Change, mean (95% CI) | P value | P value | |
| Nocturnal brachial SBP, mm Hg | −6.1 (−11.3 to −0.9) | .023 | −2.9 (−8.0 to 2.3) | .261 | .076 |
| Nocturnal brachial DBP, mm Hg | −3.8 (−6.5 to −1.1) | .008 | −2.5 (−5.3 to 0.2) | .064 | .254 |
| Nocturnal central SBPa mm Hg | −7.1 (−11.9 to −2.3) | .006 | −3.1 (−7.9 to 1.7) | .196 | .033 |
| Nocturnal central DBPa mm Hg | −4.3 (−7.2 to −1.4) | .006 | −3.1 (−6.0 to −0.2) | .037 | .342 |
Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure.
Data are expressed as mean (95% confidence interval [CI]).
P value refers to the changes in each blood pressure (BP) parameter from baseline and the comparison of morning and bedtime administration of valsartan/amlodipine combination by a linear mixed model analysis.
a
Adjusted for the change of nocturnal heart rate.