Table 3.
Univariate and multivariate analyses for the risk of predefined cardiovascular outcomes in patients with masked hypertension stratified according to their dipping profile. Composite cardiovascular outcome was a composite of new‐onset hypertension, myocardial infarction, stroke, hospitalization due to hypertension or heart failure. In multivariate analysis, the following covariates were considered: gender, age, body mass index, smoking status, hypercholesterolemia, diabetes
Parameters | CV events | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | ||
Dippers | |||||
New‐onset hypertension | 24 (36.9) | 0.976 (0.503‐1.894) | 0.942 | – | – |
Myocardial infarction | 7 (10.8) | 0.2534 (0.709‐9.054) | 0.152 | – | – |
Stroke | 1 (1.5) | 0.443 (0.045‐4.356) | 0.485 | – | – |
HT hospitalization | 6 (9.2) | 0.712 (0.249‐2.036) | 0.526 | – | – |
HF hospitalization | 3 (4.6) | 2.081 (0.338‐12.825) | 0.430 | – | – |
Nondippers | |||||
New‐onset hypertension | 24 (35.8) | 0.896 (0.462‐1.738) | 0.997 | – | – |
HT hospitalization | 6 (9.0) | 0.671 (0.235‐1.918) | 0.456 | – | – |
Reverse dippers | |||||
New‐onset hypertension | 9 (42.9) | 1.312 (0.516‐3.341) | 0.568 | – | – |
Myocardial infarction | 4 (19.0) | 4.202 (1.113‐15.868) | 0.034 | 4.317 (0.757‐24.621) | 0.100 |
Stroke | 3 (14.3) | 21.833 (2.154‐22.322) | 0.009 | 18.660 (1.056‐33.813) | 0.046 |
HT hospitalization | 5 (23.8) | 3.125 (0.973‐10.033) | 0.056 | – | – |
HF hospitalization | 2 (9.5) | 4.526 (0.710‐28.870) | 0.110 | – | – |
CV, cardiovascular; HF, heart failure; HT, hypertension.