Table 1.
Clinical characteristics of the study population
| Variable | Hypertensives n = 320 | Healthy controls n = 160 | P |
|---|---|---|---|
| Age (y) | 51 ± 11 | 48 ± 13 | .7 |
| Sex (male) (%) | 214 (67) | 106 (66) | .99 |
| Smoking (%) | 99 (31) | 48 (31) | .8 |
| Hypelipidemia (%) | 64 (20) | 33 (21) | .7 |
| BMI (kg/m2) | 30.33 ± 5.362 | 29 ± 4.085 | .5 |
| Cholesterol (mg/dL) | 216.4 ± 34.5 | 205.6 ± 35.9 | .17 |
| Triglycerides (mg/dL) | 116.9 ± 52.9 | 124.2 ± 46.7 | .54 |
| HDL (mg/dL) | 53.6 ± 13.6 | 53.5 ± 10.6 | .97 |
| LDL (mg/dL) | 140.0 ± 33.7 | 128.7 ± 33.1 | .16 |
| SBP | 147 ± 17 | 120 ± 10 | <.001 |
| DBP | 89 ± 10 | 78 ± 9 | <.001 |
| PP (mm Hg) | 52.85 ± 11.93 | 43.21 ± 12.74 | .003 |
| PBR (5‐25 μm) | 2.049 ± 0.276 | 1.769 ± 0.306 | .037 |
| PBR (5‐9 μm) | 1.156 ± 0.104 | 1.051 ± 0.132 | .036 |
| PBR (10‐19 μm) | 2.185 ± 0.327 | 1.993 ± 0.365 | .049 |
| PBR (20‐25 μm) | 2.573 ± 0.444 | 2.269 ± 0.492 | .026 |
| cSBP (mm Hg) | 142.5 ± 20.76 | 121.4 ± 12.74 | .002 |
| AI % | 27.23 ± 17.23 | 23.58 ± 16.37 | .012 |
| PWV (m/s) | 11.73 ± 2.415 | 10.21 ± 5.770 | .007 |
| CFR | 2.583 ± 0.880 | 3.311 ± 0.518 | .002 |
| LV mass (gr) | 159 ± 39 | 130 ± 37 | <.001 |
| GLS (%) | −16.97 ± 3.639 | −21.91 ± 1.543 | .005 |
| GLSr (L/s) | −1.01 ± 0.17 | −1.21 ± 0.1 | .04 |
AI, augmentation index; CFR, coronary flow reserve; cSBP, central systolic blood pressure; GLS, global longitudinal strain; GLSr, global longitudinal strain rate; PBR, perfused boundary region; PP, pulse pressure; PWV, pulse wave velocity.
Parameters are expressed as mean values ± standard deviation (SD).