Table 2.
Univariate and Multivariable analysis of the determinants in hypertensive patients
| CFR | Longitudinal strain | PWV | cSBP | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Univariate | Multivariablea | Univariate | Multivariablea | Univariate | Multivariablea | Univariate | Multivariablea | |||||||||
| Beta | P | Beta | P | Beta* | P | Beta | P | Beta | P | Beta | P | Beta | P | Beta | P | |
| Sex (female) | −.68 | .39 | −.02 | .59 | −.02 | .8 | −.03 | .7 | −.02 | .79 | −.03 | .71 | .03 | .69 | −.04 | .64 |
| Age | .06 | .45 | .05 | .55 | .22 | .005 | .18 | .04 | .22 | .005 | .18 | .04 | .40 | <.001 | .38 | <.001 |
| Heart rate | −.004 | .95 | .009 | .98 | −.04 | .66 | −.03 | .82 | −.04 | .66 | −.03 | .82 | .09 | .27 | .07 | .51 |
| BMI | .08 | .31 | .09 | .42 | .02 | .72 | .01 | .88 | .02 | .72 | .01 | .88 | .03 | .99 | .01 | .98 |
| LVM | .22 | .006 | .19 | .01 | .17 | .03 | .19 | .02 | .17 | .03 | .19 | .02 | .17 | .03 | .19 | .02 |
| Smoking | .22 | .005 | .18 | .02 | .01 | .84 | .06 | .44 | .01 | .84 | .06 | .44 | .19 | .028 | .07 | .38 |
| Hyperlipidemia | .13 | .11 | .10 | .1 | .15 | .06 | .10 | .1 | .15 | .06 | .10 | .1 | .13 | .11 | .09 | .25 |
| Office SBP | .17 | .03 | .07 | .81 | .20 | .011 | .17 | .035 | .20 | .011 | .17 | .035 | .30 | <.001 | .25 | <.001 |
| PBR5‐25 | −.19 | .02 | −.17 | .035 | .22 | .006 | .20 | .01 | .19 | .02 | .18 | .03 | .25 | .001 | .20 | .01 |
Beta, indicates standardised coefficient b; BMI, Body Mass Index; CFR, coronary flow reserve; cSBP, Central Systolic Blood Pressure; GLS, Longitudinal strain, global longitudinal of the left ventricle; LVM, left ventricular mass; PBR5‐25, perfused boundary region increased; PWV, pulse wave velocity; SBP, Systolic Blood Pressure.
PBR indicates reduced glycocalyx thickness.
a
b and P values are derived from the multivariable model including LV mass, systolic blood pressure, age, sex, heart rate, BMI, smoking, and hyperlipidemia.