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. 2021 Apr 9;70(14):523–527. doi: 10.15585/mmwr.mm7014e2

TABLE 2. Highest-frequency International Classification of Diseases, Tenth Revision (ICD-10) codes listed in death certificates with COVID-19 in Part I of death certificate and at least one diagnosis other than COVID-19 (330,198) — National Center for Health Statistics, United States, January–December 2020.

Condition (ICD-10 code) No. (% of 330,198*)
Conditions listed as chain-of-event conditions on ≥1% of death certificates
Pneumonia, unspecified (J18.9)
148,530 (45.0)
Acute respiratory failure (J96.0)
66,609 (20.2)
Respiratory failure, unspecified (J96.9)
47,045 (14.2)
Cardiac arrest, unspecified (I46.9)
36,983 (11.2)
Adult respiratory distress syndrome (J80)
36,297 (11.0)
Sepsis, unspecified (A41.9)
20,117 (6.1)
Viral pneumonia, unspecified (J12.9)
12,421 (3.8)
Asphyxia (R09.0)
10,641 (3.2)
Respiratory arrest (R09.2)
7,009 (2.1)
Conditions listed as significant contributing conditions on ≥1% of death certificates§
Essential (primary) hypertension (I10)
58,930 (17.8)
Unspecified diabetes mellitus without complications (E14.9)
34,038 (10.3)
Unspecified dementia (F03)
32,189 (9.7)
Chronic obstructive pulmonary disease, unspecified (J44.9)
24,678 (7.5)
Atherosclerotic heart disease (I25.1)
22,162 (6.7)
Type 2 diabetes mellitus without complications (E11.9)
21,038 (6.4)
Atrial fibrillation and flutter (I48)
19,784 (6.0)
Congestive heart failure (I50.0)
16,841 (5.1)
Tobacco use (F17.9)
16,424 (5.0)
Chronic kidney disease, unspecified (N18.9)
14,525 (4.4)
Alzheimer disease, unspecified (G30.9)
11,220 (3.4)
Hypertensive heart disease without (congestive) heart failure (I11.9)
9,881 (3.0)
Hyperlipidemia, unspecified (E78.5)
9,330 (2.8)
Other specified disorders of kidney and ureter (N28.8)
8,958 (2.7)
Obesity, unspecified (E66.9)
8,913 (2.7)
Chronic kidney disease, stage 5 (N18.5)
7,955 (2.4)
Stroke, not specified as hemorrhage or infarction (I64)
6,494 (2.0)
Heart failure, unspecified (I50.9)
6,436 (1.9)
Conditions listed on ≥0.5% of death certificates and not identified as known chain-of-event conditions or significant contributing conditions
Other specified general symptoms and signs (R68.8)
1,124 (0.3)
Other lack of normal physiologic development, underweight (R62.8)
734 (0.2)
Dyspnea (R06.0)
363 (0.1)
Senility (R54)
331 (0.1)
Other and unspecified infectious disease (B99.9)
247 (0.1)
Gastrointestinal hemorrhage (K92.2)
213 (0.1)
Unspecified protein energy deficiency (E46)
204 (0.1)
Influenza due to unidentified influenza virus (J11.1)
174 (0.1)
Urinary tract infection (N39.0)
150 (0.0)
Malaise and fatigue (R53)
145 (0.0)
Unspecified fall (W19)
139 (0.0)
Multiple sclerosis (G35) 124 (0.0)

* A total of 330,198 death certificates had COVID-19 listed in Part I of death certificate and at least one other diagnosis listed on the death certificate.

COVID-19 diagnosis listed in Part I of the death certificate; chain-of-event conditions listed on the same line or above the COVID-19 diagnosis in Part I of the death certificate.

§ COVID-19 diagnosis listed in Part I of the death certificate; significant contributing conditions listed below the COVID-19 line in Part I or in Part II of the death certificate.

COVID-19 diagnosis listed in Part I of the death certificate; co-occurring conditions listed anywhere on the death certificate and not identified as known chain-of-event or significant contributing conditions.