Table 1.
Allergometric tests used for patients with suspect Polyethylen glycol (PEG) and/or Polysorbate 80 (PS80) hypersensitivity, modified from Banerji et al22 We used a cleansing preparation for colon endoscopy product as source of PEG 3350,100 mg/ml.17 Methyl-prednisolone Acetate (Depo-Medrol) 40 mg/ml and Triamcinolone acetonide (Kenacort) 40 mg/ml were used to intradermally test PEG 3350 and PS80 respectively
| Step | Tested drug | Dilution | Cumulative time (min) | |
|---|---|---|---|---|
| 1 | Positive control | Histamine | 1:1 | 0 |
| Negative control | Glycerin | 1:1 | ||
| Prick test | PEG 3350 | 1:100 | ||
| Prick test | Polysorbate 80 | 1:100 | ||
| 2 | Prick test | PEG 3350 | 1:10 | 30 |
| Prick test | Polysorbate 80 | 1:10 | ||
| 3 | Prick test | PEG 3350 | 1:1 | 60 |
| 4 | Intradermal | Methyl-prednisolone Acetate (Depo-Medrol) 40 mg/ml | 1:100 | 90 |
| Intradermal | Triamcinolone acetonide (Kenacort) 40 mg/ml | 1:100 | ||
| 5 | Intradermal | Methyl-prednisolone Acetate (Depo-Medrol) 40 mg/ml | 1:10 | 120 |
| Intradermal | Triamcinolone acetonide (Kenacort) 40 mg/ml | 1:10 | ||
| 6 | Observation | 180 | ||