Table 2.

Desensitization protocol used for the administration of BNT162B2 in patients resulted positive for Polysorbate 80 or with doubtful/not evaluable allergic tests, and in those who experienced a suspect hypersensitivity reaction to the first dose of vaccine

Step	Dose (ml)	Cumulative dose (ml)	Cumulative time (min)
1	0.03	0.03	0
2	0.07	0.10	30
3	0.10	0.20	60
4	0.10	0.30	90
6	Observation		120