Table 5.

Estimated absolute increase in blood pressure (mm Hg) with 95% CI per unit of homocysteine (in ln‐transformed values) in subgroups

Conventional predisposing factors	Category	Systolic blood pressure			Diastolic blood pressure
		βa	95% CI	P interaction	βa	95% CI	P interaction
Age	<60 y	1.33	−0.47 to 3.13	.412	1.23	−0.05 to 2.50	.108
	≥60 y	2.76	1.12–4.41		1.06	−0.08 to 2.20
Sex	Female	1.71	−0.44 to 3.46	.066	0.99	−0.20 to 2.17	.576
	Male	1.20	−0.47 to 2.87		1.16	−0.14 to 2.46
BMI	Normal	1.85	0.15–3.56	.191	0.04	−0.12 to 1.20	.022
	Overweight/obese	1.38	−0.36 to 3.13		2.30	1.03–3.58
Dyslipidemia	No	0.97	−1.28 to 3.21	.065	0.04	−1.52 to 1.60	.101
	Yes	2.06	0.58–3.54		1.71	0.66–2.76
Type 2 diabetes mellitus	No	1.75	0.46–3.04	.297	1.20	0.29–2.11	.866
	Yes	1.89	−1.76 to 5.54		1.52	−1.17 to 4.21
Family history of hypertension	No	1.27	−0.16 to 2.70	.045	0.61	−0.38 to 1.60	.021
	Yes	2.59	0.26–4.92		2.46	0.78–4.14
Drinking	Nondrinkers	2.22	0.74–3.70	.264	1.02	−0.01 to 2.05	.797
	Ever‐drinkers	0.14	−1.99 to 2.26		1.31	−0.27 to 2.87
Smoking	Nonsmokers	1.79	0.39–3.19	.396	1.09	0.12–2.06	.872
	Ever‐smokers	0.73	−1.77 to 3.23		1.08	−0.86 to 3.01
Salt	≤6 g/d	1.81	−0.09 to 3.72	.679	1.10	−0.27 to 2.47	.386
	>6 g/d	1.63	0.04–3.23		1.30	0.18–2.42

Abbreviations: BMI, body mass index; CI, confidence interval.

^aAdjusted for age, sex, body mass index, fasting plasma glucose, smoking and drinking status, salt consumption, family history of hypertension, and antihypertensive medication.