Table 1.

Individual Trial Design

Study/First Author	Design	Conducting Location	Inclusion Criteria	Sample Size, No.	Mean Age, y	Men, No. (%)	Follow‐up, mo	Intervention	Mean Ablation Points
Kaltenbach10	Self‐controlled, single‐center, prospective	Frankfurt	Mild resistant hypertension, with SBP between 140 and 160 mm Hg	20	61±10.8	11 (59)	6	Conventional RDN	Left 5.6; right 5.6
Ott11	Self‐controlled, multicenter, prospective	Erlangen, Homburg, Columbus, and New York	Mild resistant hypertension, with SBP between 140 and 160 mm Hg	54	63.6±11	38 (70)	6	Conventional RDN	At least 4 each
Desch12	Randomized sham‐controlled	Lübeck, Leipzig	Mild resistant hypertension, with a mean daytime SBP on ABPM between 135 and 149 mm Hg	35/[36 as sham]	64.5±7.6 [57.4±8.6]	27 (77)/[25 (69)]	6	Conventional RDN	Left 5.5, right 5.7
Pooled	Retrospective pooled analysis	Multicenter	Mild resistant hypertension	145	62±10	101 (69.7)	6	Conventional RDN	≥4 ablation each side

Abbreviations: ABPM, ambulatory blood pressure monitoring; RDN, renal denervation; SBP, systolic blood pressure.