Table 1.
Baseline demographics in the full analysis set
| Full analysis set | eGFR < 60 mL/min/1.73 m2 | Patients with diabetes | ||||
|---|---|---|---|---|---|---|
| Olmesartan (n = 2374) | Active control (n = 2113) | Olmesartan (n = 578) | Active control (n = 387) | Olmesartan (n = 399) | Active control (n = 362) | |
| Age, y | 68.3 ± 5.0 | 68.0 ± 5.0 | 69.3 ± 5.1 | 68.9 ± 4.9 | 68.9 ± 5.0 | 68.4 ± 4.9 |
| Body mass index, kg/m2 | 27.7 ± 4.3 | 27.8 ± 4.2 | 28.3 ± 4.5 | 28.2 ± 4.7 | 28.7 ± 4.5 | 28.6 ± 4.3 |
| Sex, n (%) | ||||||
| Male | 1217 (51.3) | 1124 (53.2) | 230 (39.8) | 146 (37.7) | 227 (56.9) | 208 (57.5) |
| Female | 1157 (48.7) | 989 (46.8) | 348 (60.2) | 241 (62.3) | 172 (43.1) | 154 (42.5) |
| Race, n (%) | ||||||
| Asian | 227 (9.6) | 216 (10.2) | 17 (2.9) | 13 (3.4) | 31 (7.8) | 31 (8.6) |
| Black or African American | 60 (2.5) | 78 (3.7) | 22 (3.8) | 19 (4.9) | 16 (4.0) | 20 (5.5) |
| Hispanic or Latino | 24 (1.0) | 41 (1.9) | 0 (0.0) | 1 (0.3) | 2 (0.5) | 4 (1.1) |
| White | 2061 (86.8) | 1777 (84.1) | 539 (93.3) | 354 (91.5) | 349 (87.5) | 307 (84.8) |
| Other | 2 (0.1) | 1 (<0.1) | 0 (0.0) | 0 (0.0) | 1 (0.3) | 0 (0.0) |
| SeSBP, mm Hg | 162.9 ± 13.0 | 162.5 ± 13.1 | 164.1 ± 13.3 | 163.4 ± 13.9 | 163.3 ± 13.1 | 163.1 ± 13.4 |
| SeDBP, mm Hg | 96.9 ± 8.4 | 97.2 ± 8.2 | 95.9 ± 9.0 | 96.9 ± 8.7 | 95.2 ± 9.3 | 95.2 ± 8.4 |
| Diabetes, n (%) | 401 (16.9) | 362 (17.1) | 114 (19.7) | 75 (19.4) | 399 (100.0) | 362 (100.0) |
| eGFR, n (%) | ||||||
| >90 mL/min/1.73 m2 | 456 (19.2) | 489 (23.1) | 0 (0.0) | 0 (0.0) | 77 (19.3) | 74 (20.4) |
| >60 to ≤90 mL/min/1.73 m2 | 1319 (55.6) | 1213 (57.4) | 0 (0.0) | 0 (0.0) | 204 (51.1) | 208 (57.5) |
| >45 to ≤60 mL/min/1.73 m2 | 489 (20.6) | 340 (16.1) | 488 (84.4) | 334 (86.3) | 93 (23.3) | 65 (18.0) |
| >30 to ≤45 mL/min/1.73 m2 | 75 (3.2) | 50 (2.4) | 75 (13.0) | 50 (12.9) | 19 (4.8) | 11 (3.0) |
| >15 to ≤30 mL/min/1.73 m2 | 15 (0.6) | 3 (0.1) | 15 (2.6) | 3 (0.8) | 2 (0.5) | 0 (0.0) |
| Missing data | 20 (0.8) | 18 (0.9) | 0 (0.0) | 0 (0.0) | 4 (1.0) | 4 (1.1) |
eGFR, estimated glomerular filtration rate; SeDBP, seated diastolic blood pressure; SeSBP, seated systolic blood pressure.
Data are shown as mean ± standard deviation unless otherwise stated.