Table 1.
Low plasma ADMA (n = 100) | High plasma ADMA (n = 91) | P value | |
---|---|---|---|
Age, y | 61.0 ± 9.5 | 60.2 ± 8.4 | .559 |
Men, No. (%) | 30 (30.0) | 23 (25.3) | .286 |
Weight, kg | 71.3 ± 15.1 | 77.9 ± 15.7 | .004 |
BMI, kg/m² | 28.6 ± 5.2 | 31.5 ± 6.1 | .001 |
Waist circumference, cm | 94.2 ± 12.3 | 100.5 ± 12.7 | .001 |
Obesity, No. (%) | 33 (33.0) | 50 (54.9) | .002 |
SBP, mm Hg | 138.7 ± 17.8 | 136.6 ± 17.9 | .427 |
DBP, mm Hg | 85.3 ± 8.8 | 85.1 ± 12.9 | .884 |
Total cholesterol, mg/dL | 202.9 ± 40.7 | 196.2 ± 41.9 | .269 |
HDL cholesterol, mg/dL | 57.3 ± 15.7 | 51.8 ± 14.6 | .012 |
LDL cholesterol, mg/dL | 119.6 ± 34.9 | 109.6 ± 35.9 | .056 |
Triglycerides, mg/dL | 129.8 ± 61.9 | 178.7 ± 97.8 | <.001 |
Dyslipidemia, No. (%) | 13 (13.1) | 22 (23.9) | .041 |
Fasting glucose, mg/dL | 100.6 ± 37.5 | 108.7 ± 37.4 | .139 |
CVD, No. (%) | 10 (10) | 12 (13.2) | .322 |
Metabolic syndrome, No. (%) | 28 (28) | 61 (67) | <.001 |
Type 2 DM, No. (%) | 27 (27.0) | 42 (46.2) | .005 |
Smoking, No. (%) | 7 (7.0) | 12 (13.2) | .118 |
Family history of CVD, No. (%) | 19 (19.0) | 14 (15.4) | .321 |
Uric acid, mg/dL | 5.4 ± 1.5 | 5.8 ± 1.4 | .041 |
Creatinine, mg/dL | 0.9 ± 0.2 | 0.9 ± 0.2 | .419 |
eGFR, mL/min per 1.732 | 75.7 ± 15.8 | 71.9 ± 15.4 | .097 |
eGFR <60 mL/min per 1.732, No. (%) | 11 (11.2) | 19 (20.9) | .053 |
Albuminuria, mg/g | 14.5 ± 47.9 | 22.8 ± 67.8 | .346 |
Albuminuria >26 mg/g, No. (%) | 7 (7.4) | 12 (14.0) | .115 |
Albuminuria >300 mg/g, No. (%) | 1 (1.1) | 1 (1.2) | .726 |
CRP, mg/dL | 0.2 ± 0.3 | 0.9 ± 0.8 | <.001 |
Framingham risk score, % | 8.6 ± 7.3 | 7.9 ± 6.1 | .652 |
ADMA, asymmetric dimethylarginine; BMI, body mass index; CRP, C‐reactive protein; CVD, cardiovascular disease; DBP, diastolic blood pressure; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; SBP, systolic blood pressure. Data are expressed as mean ± standard deviation.
P value for Student t test of independent samples or χ2 test.