Table 4.
Diuretic | ARB | ACEI | β‐Blocker | CCB | |
---|---|---|---|---|---|
No. | 501 | 324 | 347 | 296 | 179 |
Age, years | 69.8 ± 0.3 | 69.3 ± 0.3 | 69.5 ± 0.3 | 68.8 ± 0.3 | 70.3 ± 0.5 |
Heart rate | 77.2 ± 1.5 | 73.8 ± 0.7 | 74.5 ± 0.7 | 68 ± 1.4d | 75.5 ± 2.0 |
Blood pressure, mm Hg | |||||
bSBP | 139.5 ± 2.57 | 141.3 ± 1.14 | 139.3 ± 1.15 | 138.3 ± 2.21 | 141.6 ± 3.30 |
bDBP | 86.7 ± 1.60b | 83.5 ± 0.70 | 82.5 ± 0.71c | 81.2 ± 1.36 | 82.9 ± 2.03 |
bPP | 54.5 ± 2.44 | 57.6 ± 1.08 | 55.6 ± 1.09 | 57.7 ± 2.09 | 59.9 ± 3.12 |
bMAP | 104.4 ± 1.66 | 102.7 ± 0.71 | 101.5 ± 0.74 | 100.3 ± 1.4 | 103.7 ± 1.07 |
cSBP | 132.7 ± 2.49 | 136.5 ± 1.08 | 132.3 ± 1.09a | 134.2 ± 1.25 | 133.8 ± 3.11 |
cDBP | 84.2 ± 0.57 | 85.0 ± 0.73 | 83.8 ± 0.67 | 83.8 ± 0.77 | 85.2 ± 1.03 |
cPP | 49.8 ± 0.67 | 51.4 ± 0.81 | 48.6 ± 0.79 | 53.3 ± 0.89 | 52.8 ± 1.20 |
cMAP | 102.3 ± 1.75 | 102.1 ± 0.76 | 100.0 ± 0.74a | 99.7 ± 1.47 | 102.5 ± 0.73 |
Arterial stiffnesse | |||||
AP, mm Hg | 14.5 ± 1.0 | 19.0 ± 0.96 | 17.5 ± 0.84 | 21.3 ± 0.66 | 15.3 ± 0.78 |
AIx, % | 31.7 ± 1.77 | 34.5 ± 0.78 | 33.4 ± 0.78 | 36.9 ± 1.50d | 30.7 ± 2.22 |
cf‐PWV, m/s | 9.72 ± 0.23 | 9.48 ± 0.11 | 9.48 ± 0.11 | 8.39 ± 0.21d | 9.47 ± 0.15 |
Values are expressed as mean ± standard error.
AP, augmentation pressure; AIx, augmentation index; bDBP, brachial diastolic blood pressure; bMAP, brachial mean arterial pressure; bPP, brachial pulse pressure; bSBP, brachial systolic blood pressure; cDBP, central diastolic blood pressure; cf‐PWV, carotid‐femoral pulse wave velocity cPP, central pulse pressure; cSBP central systolic blood pressure.
Angiotensin receptor blocker (ARB) vs angiotensin‐converting enzyme inhibitor (ACEI): P = 0.047.
β‐Blocker vs diuretic: P = 0.0093.
iECA vs diuretic: P = 0.016.
β‐Blocker vs diuretic, ACEI, ARB, and calcium channel blocker (CCB).
P < 0.05: adjusted by age and central mean arterial (cMAP).