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. 2018 Jul 24;20(9):1285–1293. doi: 10.1111/jch.13358

Table 4.

Peripheral and central blood pressure, pulse wave velocity, AIx, and antihypertensive drugs

Diuretic ARB ACEI β‐Blocker CCB
No. 501 324 347 296 179
Age, years 69.8 ± 0.3 69.3 ± 0.3 69.5 ± 0.3 68.8 ± 0.3 70.3 ± 0.5
Heart rate 77.2 ± 1.5 73.8 ± 0.7 74.5 ± 0.7 68 ± 1.4d 75.5 ± 2.0
Blood pressure, mm Hg
bSBP 139.5 ± 2.57 141.3 ± 1.14 139.3 ± 1.15 138.3 ± 2.21 141.6 ± 3.30
bDBP 86.7 ± 1.60b 83.5 ± 0.70 82.5 ± 0.71c 81.2 ± 1.36 82.9 ± 2.03
bPP 54.5 ± 2.44 57.6 ± 1.08 55.6 ± 1.09 57.7 ± 2.09 59.9 ± 3.12
bMAP 104.4 ± 1.66 102.7 ± 0.71 101.5 ± 0.74 100.3 ± 1.4 103.7 ± 1.07
cSBP 132.7 ± 2.49 136.5 ± 1.08 132.3 ± 1.09a 134.2 ± 1.25 133.8 ± 3.11
cDBP 84.2 ± 0.57 85.0 ± 0.73 83.8 ± 0.67 83.8 ± 0.77 85.2 ± 1.03
cPP 49.8 ± 0.67 51.4 ± 0.81 48.6 ± 0.79 53.3 ± 0.89 52.8 ± 1.20
cMAP 102.3 ± 1.75 102.1 ± 0.76 100.0 ± 0.74a 99.7 ± 1.47 102.5 ± 0.73
Arterial stiffnesse
AP, mm Hg 14.5 ± 1.0 19.0 ± 0.96 17.5 ± 0.84 21.3 ± 0.66 15.3 ± 0.78
AIx, % 31.7 ± 1.77 34.5 ± 0.78 33.4 ± 0.78 36.9 ± 1.50d 30.7 ± 2.22
cf‐PWV, m/s 9.72 ± 0.23 9.48 ± 0.11 9.48 ± 0.11 8.39 ± 0.21d 9.47 ± 0.15

Values are expressed as mean ± standard error.

AP, augmentation pressure; AIx, augmentation index; bDBP, brachial diastolic blood pressure; bMAP, brachial mean arterial pressure; bPP, brachial pulse pressure; bSBP, brachial systolic blood pressure; cDBP, central diastolic blood pressure; cf‐PWV, carotid‐femoral pulse wave velocity cPP, central pulse pressure; cSBP central systolic blood pressure.

a

Angiotensin receptor blocker (ARB) vs angiotensin‐converting enzyme inhibitor (ACEI): P = 0.047.

b

β‐Blocker vs diuretic: P = 0.0093.

c

iECA vs diuretic: P = 0.016.

d

β‐Blocker vs diuretic, ACEI, ARB, and calcium channel blocker (CCB).

e

P < 0.05: adjusted by age and central mean arterial (cMAP).