Table 3.
Answers to Questionnaire B
| Percent at Baseline | Percent at Follow‐Up | P Valuea | Target BPb | BP Responsec | ||
|---|---|---|---|---|---|---|
| 1. How frequently did you experience these issues or symptoms within the last 4 weeks (never/very rarely/rarely) | ||||||
| 1.1 Cold hands or feet | 64.4 | 81.7 | <.0001 | 1.07 (0.89–1.28) | 2.17 (1.38–3.41) | |
| 1.2 Tiredness | 38.4 | 65.6 | <.0001 | 1.11 (0.95–1.30) | 1.66 (1.18–2.35) | |
| 1.3 Irregular heart beat | 64.4 | 84.4 | <.0001 | 0.86 (0.73–1.02) | 1.78 (1.19–2.67) | |
| 1.4 Restlessness | 49.3 | 76.1 | <.0001 | 1.02 (0.87–1.19) | 1.65 (1.16–2.34) | |
| 1.5 Chest tightness | 71.6 | 89.2 | <.0001 | 0.91 (0.76–1.09) | 1.67 (1.10–2.53) | |
| 1.6 Head pressure | 56.9 | 84.3 | <.0001 | 0.93 (0.80–1.09) | 2.06 (1.42–2.97) | |
| 1.7 Fatigue | 45.1 | 71.6 | <.0001 | 0.96 (0.82–1.12) | 1.59 (1.12–2.25) | |
| 1.8 Headache | 52.8 | 80.2 | <.0001 | 1.09 (0.93–1.28) | 2.71 (1.81–4.04) | |
| 1.9 Drowsiness | 77.7 | 90.6 | <.0001 | 0.92 (0.76–1.12) | 1.82 (1.13–2.95) | |
| 1.10 Shortness of breath | 69.9 | 85.5 | <.0001 | 0.84 (0.70–1.01) | 1.43 (0.95–2.15) | |
| 1.11 Sleep disturbances | 53.0 | 71.5 | <.0001 | 0.97 (0.81–1.15) | 1.80 (1.19–2.70) | |
| 1.12 Sweaty hands or feet | 80.9 | 91.1 | <.0001 | 0.96 (0.78–1.19) | 3.00 (1.58–5.71) | |
| 1.13 Dizziness | 64.4 | 84.0 | <.0001 | 1.00 (0.84–1.19) | 2.07 (1.36–3.15) | |
| 1.14 Pounding heart | 67.8 | 87.4 | <.0001 | 0.84 (0.70–0.99) | 1.48 (1.01–2.19) | |
| 1.15 Swollen ankles | 73.6 | 86.9 | <.0001 | 0.86 (0.71‐1.04) | 1.38 (0.91–2.11) | |
| 2. How intensely did you feel these issues or symptoms within the last 4 weeks (did not feel it/very weakly/weakly) | ||||||
| 2.1 Cold hands or feet | 63.6 | 78.0 | <.0001 | 1.10 (0.91–1.33) | 1.79 (1.16–2.78) | |
| 2.2 Tiredness | 38.3 | 62.3 | <.0001 | 1.02 (0.87–1.21) | 1.58 (1.10–2.26) | |
| 2.3 Irregular heart beat | 65.0 | 80.8 | <.0001 | 0.92 (0.77–1.11) | 1.70 (1.11–2.59) | |
| 2.4 Restlessness | 50.5 | 72.6 | <.0001 | 1.07 (0.90–1.27) | 1.68 (1.15–2.43) | |
| 2.5 Chest tightness | 69.9 | 82.9 | <.0001 | 0.90 (0.74–1.09) | 1.75 (1.10–2.79) | |
| 2.6 Head pressure | 55.7 | 78.4 | <.0001 | 1.03 (0.87–1.22) | 2.22 (1.48–3.32) | |
| 2.7 Fatigue | 44.6 | 67.8 | <.0001 | 1.06 (0.90–1.25) | 1.94 (1.33–2.84) | |
| 2.8 Headache | 49.9 | 74.8 | <.0001 | 1.09 (0.93–1.29) | 2.25 (1.53–3.33) | |
| 2.9 Drowsiness | 74.6 | 84.0 | <.0001 | 0.95 (0.77–1.17) | 1.67 (1.01–2.74) | |
| 2.10 Shortness of breath | 67.2 | 79.6 | <.0001 | 0.90 (0.74–1.09) | 1.33 (0.87–2.02) | |
| 2.11 Sleep disturbances | 49.4 | 66.4 | <.0001 | 0.95 (0.80–1.13) | 1.63 (1.09–2.43) | |
| 2.12 Sweaty hands or feet | 78.1 | 85.5 | <.0001 | 1.06 (0.84–1.32) | 2.09 (1.18–3.71) | |
| 2.13 Dizziness | 63.4 | 79.0 | <.0001 | 0.95 (0.79–1.14) | 2.00 (1.28–3.12) | |
| 2.14 Pounding heart | 68.0 | 82.2 | <.0001 | 0.88 (0.73–1.06) | 2.16 (1.33–3.50) | |
| 2.15 Swollen ankles | 72.4 | 81.5 | <.0001 | 0.91 (0.74–1.11) | 1.58 (0.98–2.54) | |
aMcNemar test. bLikelihood of patients who achieved target blood pressure (BP) giving a more positive answer at follow‐up in comparison to baseline. cLikelihood of patients who showed a response giving a more positive answer at follow‐up in comparison to baseline.