Table 5.
Univariate and multivariate analyzes of the risk of developing treated hypertension, myocardial infarction, stroke, hospitalization for hypertension and hospitalization for heart failure during the follow‐up according to BP strata. Those parameters showing significant predictive value for the predefined outcomes at univariate analysis, were adjusted for age, gender, body mass index, smoking, dyslipidaemia, and diabetes at multivariate analysis
Parameters | Unadjusted | Adjusted—Model 1 | Adjusted—Model 2 | |||
---|---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Composite outcome (MI + Stroke + any hospitalization) | ||||||
White‐coat HT | 1.716 (1.215‐2.425) | .002 | 1.791 (1.244‐2.578) | .002 | 2.360 (1.596‐3.489) | <.001 |
Masked HT | 1.993 (1.255‐3.166) | .003 | 1.757 (1.066‐2.893) | .027 | 1.616 (0.948‐2.753) | .078 |
Sustained HT | 0.610 (0.457‐0.814) | .001 | 0.628 (0.461‐0.854) | .003 | 0.503 (0.363‐0.698) | <.001 |
Outcome myocardial infarction | ||||||
White‐coat HT | 0.753 (0.263‐2.161)) | .598 | — | — | — | — |
Masked HT | 7.739 (3.657‐16.378) | <.001 | 5.062 (2.218‐11.550) | <.001 | 4.118 (1.692‐10.019) | .002 |
Sustained HT | 0.294 (0.039‐0.624) | .001 | 0.327 (0.150‐0.714) | .005 | 0.279 (0.123‐0.636) | .002 |
Outcome stroke | ||||||
White‐coat HT | 1.206 (0.454‐3.206) | .707 | — | — | — | — |
Masked HT | 2.443 (0.834‐7.159) | .103 | — | — | — | — |
Sustained HT | 0.448 (0.207‐0.970) | .042 | 0.524 (0.237‐1.161) | .111 | 0.520 (0.234‐1.155) | .108 |
Outcome hospitalization for HT | ||||||
White‐coat HT | 1.926 (1.258‐2.947) | .003 | 1.927 (1.233‐3.013) | .04 | 2.608 (1.619‐4.202) | <.001 |
Masked HT | 2.447 (1.422‐4.210) | .001 | 2.553 (1.446‐4.508) | .001 | 2.449 (1.335‐4.491) | .004 |
Sustained HT | 0.450 (0.310‐0.653) | <.001 | 0.450 (0.302‐0.671) | <.001 | 0.325 (0.213‐0.496) | <.001 |
Outcome hospitalization for HF | ||||||
White‐coat HT | 3.130 (1.224‐8.007) | .017 | 3.449 (1.321‐9.007) | .011 | 4.334 (1.605‐11.699) | .004 |
Masked HT | 5.074 (1.803‐14.285) | .002 | 4.214 (1.449‐12.249) | .008 | 3.545 (1.160‐10.837) | .026 |
Sustained HT | 0.301 (0.114‐0.794) | .015 | 0.316 (0.117‐0.852) | .023 | 0.268 (0.096‐0.752) | .012 |
CI, confidence intervals; HF, heart failure; HT, hypertension; OR, odds ratio.