Table 2.

RV strain in patients with arterial hypertension

Reference	Sample size and subjects included in the study	Main findings
Pedrinelli et al8	89 never‐treated, non‐obese subjects with office blood pressure varying from the optimal to mildly hypertensive range	RV peak systolic strain and early diastolic strain rate reduced in the mid‐tertile of blood pressure distribution without further changes in the upper tertile. RV systolic and diastolic strain indices correlated inversely with increasing septal thickness.
Hanboly NH21	80 patients with untreated mild to moderate systemic hypertension and 40 healthy controls	RV GLS was reduced in hypertensive patients. Apical and mid segments of RV free wall were more deteriorated than basal RV segment in the hypertensive subjects
Tumuklu et al9	35 patients with arterial hypertension and 30 age‐ and sex‐adjusted control subjects	RV peak systolic strain was significantly lower in hypertensive patients with and without LV hypertrophy in comparison with normotensive controls.
Tadic et al25	174 recently diagnosed hypertensive patients	RV GLS was significantly lower in the non‐dippers. 3D RV end‐diastolic and end‐systolic volumes were increased, whereas 3D RV ejection fraction was reduced in non‐dipper hypertensive patients.
Tadic et al26	256 untreated patients (57 normotensives and 199 hypertensives)	RV mechanics is worse in night‐time and daytime‐night‐time hypertensive patients than in normotensive controls and isolated daytime hypertensive patients. 24‐h systolic blood pressure is independently associated with RV and right atrial global strain.
Tadic et al11	55 untreated hypertensive patients and 40 patients with no risk factors, similar by sex and age.	RV wall thickness, tricuspid E/e′ ratio, RV GLS, and 3D RVEF correlated with heart rate variability parameters. RV diastolic function, RV GLS, and 3D RVEF were independently associated with cardiac autonomic nervous function.
Tadic et al12	59 recently diagnosed, untreated, hypertensive patients, 62 treated subjects with well‐controlled arterial hypertension, 58 treated participants with treated but uncontrolled hypertension, and 55 controls adjusted by gender and age.	RV GLS was significantly decreased in untreated and uncontrolled hypertensive patients comparing with controls and well controlled participants. RV GLS and 3D RV stroke volume were independently associated with peak VO2.
Tadic et al34	232 hypertensive subjects	RV wall thickness was higher in concentric and concentric‐dilated LVH patients than in patients with normal LV geometry and LV concentric remodeling. RV GLS was reduced in concentric and concentric‐dilated patients compared with other hypertensive groups. 3D RV volumes were significantly higher in eccentric, dilated, and concentric‐dilated LVH hypertensive subjects. 3D RVEF was lower in these groups.

3D, three‐dimensional; E, early flow velocity across tricuspid annulus measured by pulsed Doppler; e′, early flow velocity across lateral segment of tricuspid annulus measured by tissue Doppler; GLS, global longitudinal strain; LV, left ventricle; LVH, left ventricular hypertrophy; RV, right ventricle; RVEF, right ventricular ejection fraction; VO2, peak oxygen consumption.