. 2017 May 7;19(9):890–898. doi: 10.1111/jch.13017

Table 1.

Baseline characteristics of patients by tertiles of SBP and DBP load

	Total (N=588)	Nighttime SBP load			Nighttime DBP load
	Total (N=588)	Tertile 1	Tertile 2	Tertile 3	Tertile 1	Tertile 2	Tertile 3
Limits, %		<16.7	16.7‐69.6	≥69.6	<27.3	27.3‐75.0	≥75.0
Age, y	42.8±16.7	35.9±13.7	42.7±16.9^a	49.7±16.4^a ^, ^b	35.2±15.8	46.5±17.3^a	46.6±14.3^a
Men/women	336/252	98/98	126/70	112/84	109/87	112/84	115/81
Disease course, mo	6 (1–24)	3 (1–12)	6 (1–24)	6 (1–22)^a	3 (1–12)	6 (1–24)	6 (1–24)^a
Diabetes mellitus, No. (%)	92 (15.6)	12 (6.1)	22 (11.2)^a	58 (29.6)^a ^, ^b	14 (7.1)	35 (17.9)^a	43 (21.9)^a ^, ^b
Current smoker, No. (%)	109 (18.5)	21 (10.7)	46 (23.5)^a	42 (21.4)^a	27 (13.8)	47 (24)^a	35 (17.9)^a
Alcohol intake, No. (%)	55 (9.3)	12 (6.1)	19 (9.7)	24 (12.2)	14 (7.1)	22 (11.2)	19 (9.7)
BMI, kg/m²	23.2±3.6	22.5±3.6	23.1±3.6	23.9±3.5^a	22.3±3.7	23.5±3.6^a	23.7±3.5^a
History of cardiovascular disease, No. (%)	42 (7.1)	5 (2.6)	9 (4.6)^a	28 (14.3)^a ^, ^b	4 (2)	13 (6.6)	25 (12.8)^a
eGFR, mL/min per 1.73 m²	67.8 (29.8–106.7)	101.8 (66.6–120.5)	64.3 (32.2–105.4)^a	35.9 (16.2–80.2)^a ^, ^b	105.1 (66.8–121.9)	58.2 (29.1–99.0)^a	37.0 (16.3–77.6)^a ^, ^b
Hemoglobin, g/L	122.2±24.1	129.5±19.7	124.1±24.3^a	113.0±25.1^a ^, ^b	130.6±21.2	120.7±25.0^a	115.3±23.7^a ^, ^b
Albumin, g/L	33.3±9.0	33.5±9.7	33.4±9.1	33.1±8.2	32.7±9.9	33.2±9.1	33.9±8.0
Total calcium level, mmol/L	2.2±0.2	2.2±0.2	2.2±0.2	2.2±0.2	2.2±0.2	2.2±0.2	2.2±0.2
Phosphate level, mmol/L	1.3±0.2	1.2±0.2	1.3±0.2	1.3±0.3^a	1.2±0.2	1.2±0.2	1.3±0.3^a
iPTH, pg/mL	51.9 (31.6–87.9)	38.6 (23.6–61.3)	49.0 (30.6–92.6)^a	62.6 (41.7–115.0)^a ^, ^b	39.0 (23.0–63.5)	51.1 (30.5–102.8)^a	60.3 (39.6–112.2)^a ^, ^b
Serum fasting glucose, mmol/L	5.1±1.4	4.9±1.1	5.0±1.2	5.4±1.8	4.9±1.1	5.2±1.4	5.2±1.7
Cholesterol, mmol/L	6.1±3.0	6.3±3.0	6.1±3.0	6.0±2.9	6.4±2.9	6.2±3.1	5.9±2.8
Uric acid, mmol/L	444.6±130.7	390.5±127.5	462.1±121.4^a	480.9±125.8^a	404.8±127.3	443.0±122.6^a	485.8±129.8^a ^, ^b
Blood urea nitrogen, mmol/L	6.8 (4.9–11.1)	5.2 (3.8–6.7)	7.0 (5.0–10.8)^a	9.7 (6.5–15.0)^a ^, ^b	5.0 (3.7–6.4)	7.3 (5.4–11.9)^a	9.0 (6.5–14.7)^a ^, ^b
Serum creatinine, μmol/L	107.2 (71.9–192.0)	78.7 (60.9–112.0)	118.2 (74.2–188.0)^a	159.7 (91.3–321.6)^a ^, ^b	77.3 (59.8–110.9)	118.3 (78.7–191.8)^a	165.1 (93.6–323.1)^a ^, ^b
Urinary sodium excretion, mmol/24 h	130.7±80.6	129.1±93.5	129.2±69.8	133.7±77.7	126.4±98.0	139.5±75.4	125.8±63.7
Proteinuria, g/24 h	1.7 (0.5–4.5)	0.9 (0.2–3.8)	1.7 (0.6–4.5)^a	2.2 (1.0–5.5)^a	1.2 (0.2–4.2)	1.7 (0.5–4.5)	2.0 (0.9–5.2)^a
Clinic SBP, mm Hg	140.2±22.9	125.7±16.6	138.6±17.2^a	156.4±23.1^a ^, ^b	17.3±1.2	140.4±20.5^a	153.4±22.5^a ^, ^b
Clinic DBP, mm Hg	85.4±13.2	79.3±10.7	85.9±11.6^a	91.0±14.4^a ^, ^b	78.1±10.0	84.4±11.2^a	93.6±13.3^a ^, ^b
24‐h SBP, mm Hg	129.0±17.2	112.4±8.1	128.5±9.0^a	146.3±13.0^a ^, ^b	114.2±10.5	129.7±12.8^a	143.3±13.9^a ^, ^b
24‐h DBP, mm Hg	77.8±10.0	69.3±5.8	78.4±6.9^a	85.6±9.3^a ^, ^b	68.5±5.2	77.3±5.7^a	87.6±7.7^a ^, ^b
Saytime SBP, mm Hg	130.6±17.2	114.5±8.9	130.4±9.9^a	146.9±13.8^a ^, ^b	116.4±11.0	131.1±13.4^a	144.2±14.2^a ^, ^b
Daytime DBP, mm Hg	79.0±10.1	70.8±6.1	79.8±7.5^a	86.2±9.6^a ^, ^b	70.1±5.6	78.5±6.6^a	88.2±8.2^a ^, ^b
Nighttime SBP, mm Hg	121.0±19.6	101.2±7.3	119.1±7.2^a	142.6±13.5^a ^, ^b	103.2±10.5	121.6±13.0^a	138.1±16.1^a ^, ^b
Nighttime DBP, mm Hg	71.8±11.6	61.4±6.6	71.5±6.5^a	82.4±9.7^a ^, ^b	59.9±5.3	71.2±3.9^a	84.2±7.8^a ^, ^b
Receiving no antihypertensive drugs, No. (%)	147 (25)	66 (33.7)	57 (29.1)^a	24 (12.2)^a ^, ^b	71 (36.2)	48 (24.5)^a	28 (14.3)^a ^, ^b
RAS blockade, No. (%)	341 (58.0)	122 (62.2)	110 (56.1)	109 (55.6)	118 (60.2)	115 (58.7)	108 (55.1)
Calcium channel blocker, No. (%)	196 (33.3)	14 (7.1)	59 (30.1)^a	123 (62.8)^a ^, ^b	16 (8.2)	66 (33.7)^a	114 (58.2)^a ^, ^b
α‐Blocker, No. (%)	46 (7.8)	2 (1)	8 (4.1)	36 (18.4)^a ^, ^b	4 (2)	12 (6.1)	30 (15.3)^a
β‐Blocker, No. (%)	94 (16.0)	9 (4.6)	28 (14.3)^a	57 (29.1)^a ^, ^b	8 (4.1)	34 (17.3)^a	52 (26.5)^a
Statins, No. (%)	103 (17.5)	35 (17.9)	24 (12.2)	44 (22.4)^b	35 (17.9)	26 (13.3)	42 (21.4)

Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; iPTH, intact parathyroid hormone; RAS, renin‐angiotensin system; SBP, systolic blood pressure.

Indicated comparison with tertile 1, P<.05.

Indicated comparison with tertile 2, P<.05. P value for multiple comparisons was corrected according to the Bonferroni method (3 comparisons).