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. 2021 Apr 8;17(4):e1009406. doi: 10.1371/journal.pgen.1009406

Fig 3. PLD3 expression correlates with neuropathology and cognitive trajectory.

Fig 3

Human hippocampal PLD3 mRNA counts (in transcripts per million, TPM) were obtained from the ROS/MAP cohort A. Regression analysis reveals across all clinical diagnoses, higher levels of PLD3 appear protective with respect to lower β-amyloid plaque counts in prefrontal cortex. B. Protective effect of PLD3 expression on β-amyloid burden is stronger in women. C. Across all clinical diagnoses, higher levels of PLD3 correlate with slower rates of cognitive decline. D. PLD3 expression correlates with memory function.