Table 2. The microbiome difference depending on disease subtype and tissue type.

Disease subtype	P-value
UT_CRSwNP vs. UT_CRSsNP	0.003
UT_CRSwNP vs. UT_Control	0.006
UT_CRSsNP vs. UT_Control	0.335
Tissue type	P-value
NP vs. UT_CRSwNP	0.002
NP vs. UT_Control	0.002

The P-values were calculated using permutational multivariate analysis of variance (PERMANOVA) using weighted UniFrac distance. Abbreviations: NP, nasal polyp; UT_CRSwNP, uncinate tissue from chronic rhinosinusitis with nasal polyp; UT_CRSsNP, uncinate tissue from chronic rhinosinusitis without nasal polyp.