Table 1. Baseline characteristics of patients with IgA nephropathy.
| Baseline Characteristics | n = 130 (%) | Mean ± SD or Median (IQR) |
|---|---|---|
| Age (years) | 38.0 ± 14.0 | |
| Female (%) | 74 (56.9) | |
| Ethnicity (%) | ||
| Malay | 71 (54.6) | |
| Chinese | 51 (39.2) | |
| Indian | 2 (1.5) | |
| Others | 6 (4.6) | |
| Hypertensive subjects (%) | 84 (64.6) | |
| SBP (mm Hg) | 137 (126 to 154) | |
| DBP (mm Hg) | 81 (74 to 95) | |
| MAP (mm Hg) | 99 (91 to 113) | |
| Clinical Presentation | ||
| Asymptomatic (%) | 76 (58.5) | |
| Urinary abnormality | 76 (58.5) | |
| Abnormal creatinine | 18 (13.8) | |
| Newly diagnosed hypertension | 28 (21.5) | |
| Symptomatic (%) | 54 (41.5) | |
| Nephrotic Syndrome | 35 (26.9) | |
| Nephritic Syndrome | 11 (8.5) | |
| Gross Hematuria | 8 (6.2) | |
| Laboratory test | ||
| Proteinuria (g/day) | 2.4 (1.4 to 5.1) | |
| Proteinuria g/day (%) | ||
| <0.5 | 6 (4.6) | |
| ≥0.5 <1.0 | 14 (10.8) | |
| ≥1.0 <3.0 | 53 (40.8) | |
| ≥ 3.0 | 57 (43.8) | |
| eGFR (ml/min per 1.732) | 75.2 (49.3 to 101.4) | |
| CKD Stage (%) | ||
| I | 47 (36.2) | |
| II | 36 (27.7) | |
| III | 31 (23.8) | |
| IV | 15 (11.5) | |
| V | 1 (0.8) | |
| Treatment before renal biopsy (%) | 54 (41.5) | |
| Immunosuppressive treatment (%) | 11 (8.5) | |
| RAAS Blockade (%) | 30 (23.1) | |
SBP: systolic blood pressure, DBP: diastolic blood pressure, MAP: mean arterial pressure, eGFR: estimated glomerular filtration rate, CKD: Chronic kidney disease, RAAS: renin-angiotensin-aldosterone system.
Symptomatic refers to predominant clinical presenting syndrome, based on symptoms as well as laboratory criteria, i.e., Nephrotic Syndrome, Nephritic Syndrome, or Gross Hematuria.
Results were expressed as mean ± SD, median (interquartile range), or percentage.